product summary
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company name :
MyBioSource
product type :
protein
product name :
CLC, 1-142aa, Human, His tag, E Coli
catalog :
MBS204093
quantity :
0.1 mg
price :
310 USD
more info or order :
product information
catalog number :
MBS204093
products type :
Recombinant Protein
products full name :
CLC, 1-142aa, Human, His tag, E Coli
products short name :
CLC
products name syn :
Eosinophil lysophospholipase; Galectin 10; Gal-10; GAL10; LGALS10; LGALS10A; LPPL
other names :
galectin-10; Galectin-10; galectin-10; Charcot-Leyden crystal protein; eosinophil lysophospholipase; galectin 10; lectin, galactoside-binding, soluble, 10; lysolecithin acylhydrolase; Charcot-Leyden crystal galectin; Charcot-Leyden crystal protein; CLC; Eosinophil lysophospholipase; Lysolecithin acylhydrolase
products gene name :
CLC
other gene names :
CLC; CLC; GAL10; Gal-10; LGALS10; LGALS10A; LPPL_HUMAN; LGALS10; LGALS10A; Gal-10; CLC
uniprot entry name :
LEG10_HUMAN
sequence length :
142
sequence :
MGSSHHHHHH SSGLVPRGSH MSLLPVPYTE AASLSTGSTV TIKGRPLACF LNEPYLQVDF HTEMKEESDI VFHFQVCFGR RVVMNSREYG AWKQQVESKN MPFQDGQEFE LSISVLPDKY QVMVNGQSSY TFDHRIKPEA VKMVQVWRDI SLTKFNVSYL KR
purity :
> 90% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Signal Transduction
products description :
Eosinophil lysophospholipase (CLC), also known as Galectin 10, act on biological membranes to regulate the multifunctional lysophospholipids. CLC is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. Recombinant human CLC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Gieich G J., et al. (1976) J Clin Invest. 57:633-640. Swaminathan G J., et al. (1999) Biochemistry 38:13837-13843.
ncbi gi num :
20357559
ncbi acc num :
NP_001819
ncbi gb acc num :
NM_001828.5
ncbi mol weight :
18.6 kDa (162aa) confirmed by MALDI-TOF
ncbi summary :
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. [provided by RefSeq, Jul 2008]
uniprot summary :
CLC: May have both lysophospholipase and carbohydrate-binding activities. Protein type: Phospholipase; EC 3.1.1.5. Chromosomal Location of Human Ortholog: 19q13.1. Cellular Component: cytosol. Molecular Function: protein binding; carbohydrate binding; lysophospholipase activity. Biological Process: regulation of activated T cell proliferation; regulation of T cell cytokine production; multicellular organismal development; regulation of T cell anergy
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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