HRP-Linked Polyclonal Antibody to Galectin 9 (GAL9) | MyBioSource MBS2040918 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

HRP-Linked Polyclonal Antibody to Galectin 9 (GAL9)

catalog :

MBS2040918

quantity :

0.1 mg

price :

255 USD

clonality :

polyclonal

host :

rabbit

conjugate :

HRP

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2040918

products type :

Antibody

products full name :

HRP-Linked Polyclonal Antibody to Galectin 9 (GAL9)

products short name :

[Galectin 9 (GAL9)]

products name syn :

[LGALS9; Ecalectin; Lectin, Galactoside-Binding Soluble 9; Tumor antigen HOM-HD-21]

other names :

[galectin-9; Galectin-9; galectin-9; galectin 9; Ecalectin; Tumor antigen HOM-HD-21]

products gene name :

[GAL9]

other gene names :

[LGALS9; LGALS9; HUAT; LGALS9A; Gal-9]

clonality :

Polyclonal

host :

Rabbit

purity :

Antigen-specific Affinity Chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

1 mg/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Western Blot(WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP).

app notes :

Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user.

other info1 :

Organism Species: Homo sapiens (Human). Source: Antibody labeling. Label: HRP. Traits: Liquid. Immunogen: Recombinant GAL9 (Met1~Thr355) expressed in E.coli.

other info2 :

Unconjugated Antibody: The unconjugated antibody version of this item is also available as catalog #MBS2027237

ncbi gi num :

18148434

ncbi acc num :

BAB83625.1

ncbi pathways :

Cytokine Signaling In Immune System Pathway (1269310); Immune System Pathway (1269170); Interleukin-2 Signaling Pathway (1269321); Signaling By Interleukins Pathway (1269318)

ncbi summary :

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

galectin-9: Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 17q11.2. Cellular Component: cytoplasm; extracellular space; intracellular; nucleus. Molecular Function: carbohydrate binding; disaccharide binding; enzyme binding; galactose binding; signal transducer activity. Biological Process: activation of NF-kappaB transcription factor; female pregnancy; inflammatory response; maternal process involved in pregnancy; natural killer cell tolerance induction; negative regulation of activated T cell proliferation; negative regulation of chemokine production; negative regulation of interferon-gamma production; negative regulation of mast cell degranulation; negative regulation of natural killer cell mediated cytotoxicity; negative regulation of tumor necrosis factor production; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interleukin-1 beta secretion; positive regulation of interleukin-4 production; positive regulation of NF-kappaB import into nucleus; positive regulation of virion penetration into host cell; regulation of interleukin-4 production; regulation of interleukin-5 production; response to lipopolysaccharide; toll-like receptor 2 signaling pathway; toll-like receptor 4 signaling pathway

size1 :

0.1 mg

price1 :

255 USD

size2 :

0.2 mg

price2 :

395

size3 :

1 mg

price3 :

935

more info or order :

MyBioSource product webpage