product summary
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company name :
MyBioSource
product type :
protein
product name :
CLPP, 57-277aa, Human, E Coli
catalog :
MBS204060
quantity :
0.05 mg
price :
375 USD
more info or order :
product information
catalog number :
MBS204060
products type :
Recombinant Protein
products full name :
CLPP, 57-277aa, Human, E Coli
products short name :
CLPP
products name syn :
Putative ATP-dependent Clp protease proteolytic subunit mitochondrial; Endopeptidase Clp
other names :
ATP-dependent Clp protease proteolytic subunit, mitochondrial; ATP-dependent Clp protease proteolytic subunit, mitochondrial; ATP-dependent Clp protease proteolytic subunit, mitochondrial; ATP-dependent protease ClpAP, proteolytic subunit, human; ClpP caseinolytic peptidase ATP-dependent, proteolytic subunit; ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog; ClpP caseinolytic protease, ATP-dependent, proteolytic subunit homolog; endopeptidase Clp; putative ATP-dependent Clp protease proteolytic subunit, mitochondrial; caseinolytic mitochondrial matrix peptidase proteolytic subunit; Endopeptidase Clp
products gene name :
CLPP
other gene names :
CLPP; CLPP; DFNB81; PRLTS3
uniprot entry name :
CLPP_HUMAN
sequence length :
277
sequence :
MPLIPIVVEQ TGRGERAYDI YSRLLRERIV CVMGPIDDSV ASLVIAQLLF LQSESNKKPI HMYINSPGGV VTAGLAIYDT MQYILNPICT WCVGQAASMG SLLLAAGTPG MRHSLPNSRI MIHQPSGGAR GQATDIAIQA EEIMKLKKQL YNIYAKHTKQ SLQVIESAME RDRYMSPMEA QEFGILDKVL VHPPQDGEDE PTLVQKEPVE AAPAAEPVPA ST
purity :
> 90% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing 2mM DTT, 20% glycerol, 100mM NaCl
concentration :
0.5mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli
products categories :
Metabolism
products description :
CLPP (ATP-dependent Clp protease proteolytic subunit) belongs to the peptidase family S14. CLPP cleaves peptides in various proteins in a process that requires ATP hydrolysis. CLPP, the catalytic core of the Clp proteolytic complex, is widely involved in many cellular processes via the regulation of intracellular protein quality. CLPP may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Recombinant human CLPP protein was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Li XH., et al (2010) BMC Microbiol. 19;10:54. Kang, S.G., et al (2002) J. Biol. Chem. 277: 21095-21102.
ncbi gi num :
5174419
ncbi acc num :
NP_006003
ncbi gb acc num :
NM_006012.2
ncbi mol weight :
24.2kDa (222aa), confirmed by MALDI-TOF
ncbi summary :
The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. [provided by RefSeq, Jul 2008]
uniprot summary :
CLPP: Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Belongs to the peptidase S14 family. Protein type: Mitochondrial; Protease; EC 3.4.21.92. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: mitochondrion; mitochondrial matrix. Molecular Function: peptidase activity; identical protein binding; protein binding; serine-type endopeptidase activity. Biological Process: proteolysis involved in cellular protein catabolic process; protein homooligomerization. Disease: Perrault Syndrome 3
size1 :
0.05 mg
price1 :
375 USD
size2 :
0.25 mg
price2 :
925
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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