catalog number :
MBS204017
products type :
Recombinant Protein
products full name :
ACYP1, 1-99aa, Human, His tag, E Coli
products short name :
ACYP1
products name syn :
Acylphosphatase-1; ACYPE; erythrocyte acylphosphatase
other names :
acylphosphatase-1 isoform a; Acylphosphatase-1; acylphosphatase-1; acylphosphatase, erythrocyte isozyme; acylphosphatase, organ-common type isozyme; acylphosphate phosphohydrolase 1; acylphosphatase 1, erythrocyte (common) type; Acylphosphatase, erythrocyte isozyme; Acylphosphatase, organ-common type isozyme; Acylphosphate phosphohydrolase 1
products gene name :
ACYP1
other gene names :
ACYP1; ACYP1; ACYPE; ACYPE
uniprot entry name :
ACYP1_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MGSMAEGNTL ISVDYEIFGK VQGVFFRKHT QAEGKKLGLV GWVQNTDRGT VQGQLQGPIS KVRHMQEWLE TRGSPKSHID KANFNNEKVI LKLDYSDFQI VK
purity :
> 90% by SDS - PAGE
form :
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
concentration :
1.0 mg/ml (determined by BCA assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Metabolism
products description :
ACYP1, also known as erythrocyte acylphosphatase, is a cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two acylphophatase isoenzymes exist: ACYP1 and ACYP2. The two isoenzymes share 60% homology and have the same substrate specificity, although ACYP1 has higher catalytic activity than ACYP2. Recombinant human ACYP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
products references :
Fiaschi T, et al. (1995). FEBS Lett. 367:145-8. Paoli P., et al. (2003). J. Biol. Chem. 278: 194-199.
ncbi gb acc num :
NM_001107.4
ncbi mol weight :
13.6 kDa (122aa), confirmed by MALDI-TOF
ncbi pathways :
Pyruvate Metabolism Pathway 82998!!Pyruvate Metabolism Pathway 373
ncbi summary :
This gene is a member of the acylphosphatase family. The encoded protein is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated and described based on their tissue localization: erythrocyte (common) type acylphosphatase encoded by this gene, and muscle type acylphosphatase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]