catalog number :
MBS204015
products type :
Recombinant Protein
products full name :
S100A10, 1-97aa, Human, His tag, E Coli
products short name :
S100A10
products name syn :
S100 calcium binding protein A10; 42C; ANX2L; ANX2LG; CAL1; CLP11 GP11; p10; P11
other names :
protein S100-A10; Protein S100-A10; protein S100-A10; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); annexin II tetramer (AIIt) p11 subunit; calpactin I light chain; calpactin-1 light chain; cellular ligand of annexin II; S100 calcium binding protein A10; Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11
products gene name :
S100A10
other gene names :
S100A10; S100A10; 42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG; ANX2LG; CAL1L; CLP11
uniprot entry name :
S10AA_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MPSQMEHAME TMMFTFHKFA GDKGYLTKED LRVLMEKEFP GFLENQKDPL AVDKIMKDLD QCRDGKVGFQ SFFSLIAGLT IACNDYFVVH MKQKGKK
purity :
> 90% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol,0.1M NaCl, 0.1mM PMSF
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Signal Transduction
products description :
S100 calcium binding protein A10, also known S100A10, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A10 is primarily found in mast cells as heterotetrameric complexes that are present intracellularly at the plasma membrane or on the extracellular cell surface. Extracellular S100A10 is a key plasminogen receptor that plays an important role in cellular plasmin production and cellular invasiveness. Recombinant human S100A10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
EI Rifai W., et al. (2000) Cancer Res. 62:6823-6826. Gattaz W F., et al. (2000) Schizo Res. 43:91-5.
ncbi gb acc num :
NM_002966.2
ncbi mol weight :
13.3 kDa (117aa) confirmed by MALDI-TOF
ncbi pathways :
Dissolution Of Fibrin Clot Pathway 106061!!Hemostasis Pathway 106028!!Orphan Transporters Pathway 1127546!!Prostaglandin Synthesis And Regulation Pathway 198912!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008]