protein

S100A6, 1-90aa, Human, His tag, E Coli

MBS203985

0.1 mg

310 USD

Recombinant Protein

S100A6, 1-90aa, Human, His tag, E Coli

S100A6

S100 calcium binding protein A6; 2A9; 5B10; CABP; CACY; PRA

protein S100-A6; Protein S100-A6; protein S100-A6; MLN 4; S100 calcium-binding protein A6 (calcyclin); growth factor-inducible protein 2A9; prolactin receptor-associated protein; S100 calcium binding protein A6; Calcyclin; Growth factor-inducible protein 2A9; MLN 4; Prolactin receptor-associated protein; PRA; S100 calcium-binding protein A6

S100A6

S100A6; S100A6; 2A9; PRA; 5B10; CABP; CACY; CACY; PRA

S10A6_HUMAN

90

MGSSHHHHHH SSGLVPRGSH MACPLDQAIG LLVAIFHKYS GREGDKHTLS KKELKELIQK ELTIGSKLQD AEIARLMEDL DRNKDQEVNF QEYVTFLGAL ALIYNEALKG

> 95% by SDS - PAGE

Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 30% glycerol

1 mg/ml (determined by Bradford assay)

Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.

SDS-PAGE

Antigen Species: Human. Tag: His-tag

Expression System: E Coli

Cell Cycle

S100A6, also known as CACY, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. This protein may function as calcium sensor and contribute to cellular calcium signaling. Recombinant human S100A6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Kim EH., et al. (2010) Oncogene. 29(33):4725-31. Van Dieck J., et al. (2009) J Biol Chem. 284(20):13804-11.

7657532

NP_055439

NM_014624.3

12.3 kDa (110aa) confirmed by MALDI-TOF

Gastric Cancer Network 2 Pathway (760637); Prostaglandin Synthesis And Regulation Pathway (198912)

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]

S100A6: May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. Belongs to the S-100 family. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: ruffle; extrinsic to internal side of plasma membrane; perinuclear region of cytoplasm; cytoplasm; nuclear envelope; nucleus; cytosol. Molecular Function: protein binding; protein homodimerization activity; zinc ion binding; ion transmembrane transporter activity; calcium ion binding; tropomyosin binding; calcium-dependent protein binding. Biological Process: positive regulation of fibroblast proliferation; axonogenesis; signal transduction

0.1 mg

310 USD

0.5 mg

720