product summary
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company name :
MyBioSource
product type :
protein
product name :
CBR4, 1-237aa, Human, His tag, E Coli
catalog :
MBS203931
quantity :
0.05 mg
price :
375 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203931
products type :
Recombinant Protein
products full name :
CBR4, 1-237aa, Human, His tag, E Coli
products short name :
CBR4
products name syn :
Carbonyl reductase family member 4; Quinone reductase CBR4; 3-oxoacyl-[acyl-carrier-protein] reductase
other names :
Carbonyl reductase 4; Carbonyl reductase family member 4; carbonyl reductase family member 4; 3-oxoacyl-[acyl-carrier-protein] reductase; carbonic reductase 4; quinone reductase CBR4; short chain dehydrogenase/reductase family 45C, member 1; carbonyl reductase 4; 3-oxoacyl-[acyl-carrier-protein] reductase (EC:1.1.1.-); Quinone reductase CBR4
products gene name :
CBR4
other gene names :
CBR4; CBR4; SDR45C1
uniprot entry name :
CBR4_HUMAN
sequence length :
237
sequence :
MGSSHHHHHH SSGLVPRGSH MDKVCAVFGG SRGIGRAVAQ LMARKGYRLA VIARNLEGAK AAAGDLGGDH LAFSCDVAKE HDVQNTFEEM EKHLGRVNFL VNAAGINRDG LLVRTKTEDM VSQLHTNLLG SMLTCKAAMR TMIQQQGGSI VNVGSIVGLK GNSGQSVYSA SKGGLVGFSR ALAKEVARKK IRVNVVAPGF VHTDMTKDLK EEHLKKNIPL GRFGETIEVA HAVVFLLESP YITGHVLVVD GGLQLIL
purity :
> 95% by SDS - PAGE
form :
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 5mM DTT, 200mM NaCl
concentration :
0.5mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Redox Proteins
products description :
CBR4 belongs to the short-chain dehydrogenase/reductase family. The formation of heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity for o- and p-quinones. It plays a role in biosynthesis of fatty acids in mitochondria and has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro). Recombinant human CBR4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Endo S., et al. (2008) Biochem Biophys Res Commun. 26;377(4):1326-30. Chen Z., et al. (2009) FASEB J. 23:3682-3691.
ncbi gi num :
18314621
ncbi acc num :
AAH21973
ncbi mol weight :
27.5kDa (257aa) confirmed by MALDI-TOF
uniprot summary :
CBR4: The heteroteramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.1.1.-; Mitochondrial; Oxidoreductase; EC 1.-.-.-. Chromosomal Location of Human Ortholog: 4q32.3. Cellular Component: mitochondrial matrix. Molecular Function: protein binding; NAD(P)H dehydrogenase (quinone) activity; NADPH dehydrogenase (quinone) activity; quinone binding. Biological Process: fatty acid biosynthetic process; protein homotetramerization
size1 :
0.05 mg
price1 :
375 USD
size2 :
0.25 mg
price2 :
925
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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