product summary
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company name :
MyBioSource
product type :
antibody
product name :
HRP-Linked Polyclonal Antibody to Alpha-Fetoprotein (aFP)
catalog :
MBS2038911
quantity :
0.1 mg
price :
190 USD
clonality :
polyclonal
host :
rabbit
conjugate :
HRP
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2038911 image 1
Knockout Validation: Lane 1: Wild-type HepG2 cell lysate;;Lane 2: aFP knockout HepG2 cell lysate;;Predicted MW: 69kDa ;Observed MW: 70kDa;Primary Ab: 2ug/ml Rabbit Anti-Human aFP Ab;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;(#MBS2086047)
product information
catalog number :
MBS2038911
products type :
Antibody
products full name :
HRP-Linked Polyclonal Antibody to Alpha-Fetoprotein (aFP)
products short name :
[Alpha-Fetoprotein (aFP)]
products name syn :
[A-FP; FETA; HPAFP; Alpha-Fetoglobulin; Alpha-1-fetoprotein]
other names :
[alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; alpha fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin]
products gene name :
[aFP]
other gene names :
[AFP; AFP; AFPD; FETA; HPAFP; HPAFP]
clonality :
Polyclonal
host :
Rabbit
purity :
Antigen-specific Affinity Chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
concentration :
0.81 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB),Immunohistochemistry (IHC),Immunocytochemistry (ICC)
app notes :
Western blotting: 0.5-2 ug/mL;1:400-1600. Immunohistochemistry: 5-20 ug/mL;1:40-160. Immunocytochemistry: 5-20 ug/mL;1:40-160. Optimal working dilutions must be determined by end user.
image1 heading :
Knockout Validation
other info1 :
Organism Species: Homo sapiens (Human). Source: Antibody labeling. Label: HRP. Traits: Liquid. Immunogen: Recombinant aFP (Ile31~Pro171) expressed in E.coli.
ncbi gi num :
4501989
ncbi acc num :
NP_001125.1
ncbi gb acc num :
NM_001134.2
uniprot acc num :
P02771
ncbi pathways :
Direct P53 Effectors Pathway (137939); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Glucocorticoid Receptor Regulatory Network Pathway (138014); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388)
ncbi summary :
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
uniprot summary :
AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: cytoplasm. Molecular Function: protein binding. Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of
size1 :
0.1 mg
price1 :
190 USD
size2 :
0.2 mg
price2 :
265
size3 :
1 mg
price3 :
630
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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