ALDOC, 1-364aa, Human, His tag, E Coli | MyBioSource MBS203838 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

ALDOC, 1-364aa, Human, His tag, E Coli

catalog :

MBS203838

quantity :

0.1 mg

price :

310 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS203838

products type :

Recombinant Protein

products full name :

ALDOC, 1-364aa, Human, His tag, E Coli

products short name :

ALDOC

products name syn :

Aldolase C; fructose-bisphosphate; ALDC

other names :

fructose-bisphosphate aldolase C; Fructose-bisphosphate aldolase C; fructose-bisphosphate aldolase C; aldolase 3; brain-type aldolase; fructoaldolase C; fructose-1,6-biphosphate triosephosphate lyase; aldolase C, fructose-bisphosphate; Brain-type aldolase

products gene name :

ALDOC

other gene names :

ALDOC; ALDOC; ALDC; ALDC

uniprot entry name :

ALDOC_HUMAN

sequence length :

364

sequence :

MGSSHHHHHH SSGLVPRGSH MPHSYPALSA EQKKELSDIA LRIVAPGKGI LAADESVGSM AKRLSQIGVE NTEENRRLYR QVLFSADDRV KKCIGGVIFF HETLYQKDDN GVPFVRTIQD KGIVVGIKVD KGVVPLAGTD GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKISERTPS ALAILENANV LARYASICQQ NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HVYLEGTLLK PNMVTPGHAC PIKYTPEEIA MATVTALRRT VPPAVPGVTF LSGGQSEEEA SFNLNAINRC PLPRPWALTF SYGRALQASA LNAWRGQRDN AGAATEEFIK RAEVNGLAAQ GKYEGSGEDG GAAAQSLYIA NHAY

purity :

> 95 % by SDS - PAGE

form :

Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.

concentration :

1 mg/ml (determined by Bradford assay)

storage stability :

Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.

tested application :

SDS-PAGE

other info1 :

Antigen Species: Human. Tag: His-tag

other info2 :

Expression System: E Coli

products categories :

Cancer

products description :

ALDOC, also known as aldolase C, is a member of the class I fructose-biphosphate aldolase family. This protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehydes respectively. It is expressed specifically in the hippocampus and Purkinje cells of the brain. Recombinant human ALDOC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

products references :

Wang CF., et al. (2007) Anim Genet. 38(3):203-10. Arakaki TL., et al. (2004) Protein Sci. 13(12):3077-84.

ncbi gi num :

4885063

ncbi acc num :

NP_005156

ncbi gb acc num :

NM_005165.2

ncbi mol weight :

41.6 kDa (384aa), confirmed by MALDI-TOF

ncbi pathways :

Biosynthesis Of Amino Acids Pathway (790012); Biosynthesis Of Amino Acids Pathway (795174); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); Disease Pathway (530764); Fructose And Mannose Metabolism Pathway (82930); Fructose And Mannose Metabolism Pathway (291); Gluconeogenesis Pathway (106204); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (413342); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (468196)

ncbi summary :

This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

uniprot summary :

ALDOC: a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]. Protein type: EC 4.1.2.13; Carbohydrate Metabolism - fructose and mannose; Lyase; Carbohydrate Metabolism - pentose phosphate pathway; Carbohydrate Metabolism - glycolysis and gluconeogenesis. Chromosomal Location of Human Ortholog: 17cen-q12. Cellular Component: cytoskeleton; mitochondrion; axon; cytosol. Molecular Function: protein binding; cytoskeletal protein binding; fructose-bisphosphate aldolase activity. Biological Process: organ regeneration; glycolysis; apoptosis; glucose metabolic process; pathogenesis; response to organic nitrogen; response to organic cyclic substance; gluconeogenesis; protein homotetramerization; fructose 1,6-bisphosphate metabolic process; epithelial cell differentiation; carbohydrate metabolic process; response to hypoxia; protein heterotetramerization; aging; fructose metabolic process

size1 :

0.1 mg

price1 :

310 USD

size2 :

0.5 mg

price2 :

720

more info or order :

MyBioSource product webpage