product summary
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company name :
MyBioSource
product type :
protein
product name :
PFDN1, 14-122aa, Human, His tag, E Coli
catalog :
MBS203820
quantity :
0.01 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203820
products type :
Recombinant Protein
products full name :
PFDN1, 14-122aa, Human, His tag, E Coli
products short name :
PFDN1
products name syn :
Prefoldin subunit 1; PDF; PFD1
other names :
prefoldin subunit 1; Prefoldin subunit 1; prefoldin subunit 1; prefoldin 1; prefoldin subunit 1
products gene name :
PFDN1
other gene names :
PFDN1; PFDN1; PDF; PFD1; PFD1
uniprot entry name :
PFD1_HUMAN
sequence length :
122
sequence :
MGSSHHHHHH SSGLVPRGSH MTELQAKVID TQQKVKLADI QIEQLNRTKK HAHLTDTEIM TLVDETNMYE GVGRMFILQS KEAIHSQLLE KQKIAEEKIK ELEQKKSYLE RSVKEAEDNI REMLMARRAQ
purity :
> 90% by SDS - PAGE
form :
Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 20% Glycerol
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Heat Shock Proteins
products description :
PFDN1 is one of sixsubunits of prefoldin, a heterohexameric chaperone protein which assists in the correct folding of other proteins. This protein delivers nonnative target proteins, principally actins and tubulins, to the eukaryotic cytosolic chaperonin for facilitated folding. Defects in PFDN1 displayed phenotypes characteristic of defects in cytoskeletal function, including manifestations of ciliary dyskinesia, neuronal loss, and defects in B and T cell development and function. Recombinant human PFDN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
products references :
Ruley HE., et al. (2008) J Immunol. 181(1):476-84. Cowan NJ., et al (2004) J Biol Chem. 279(6):4196-203.
ncbi gi num :
21536449
ncbi acc num :
NP_002613
ncbi gb acc num :
NM_002622.4
ncbi mol weight :
15.0kDa (130aa), confirmed by MALDI-TOF
ncbi pathways :
Chaperonin-mediated Protein Folding Pathway 106242!!Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway 106243!!Metabolism Of Proteins Pathway 106230!!Prefoldin Mediated Transfer Of Substrate To CCT/TriC Pathway 106244!!Protein Folding Pathway 106241
ncbi summary :
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008]
size :
0.01 mg
price :
310 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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