product summary
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company name :
MyBioSource
product type :
protein
product name :
MAPRE3, 1-281aa, Human, His tag, E Coli
catalog :
MBS203749
quantity :
0.1 mg
price :
310 USD
more info or order :
product information
catalog number :
MBS203749
products type :
Recombinant Protein
products full name :
MAPRE3, 1-281aa, Human, His tag, E Coli
products short name :
MAPRE3
products name syn :
microtubule-associated protein RP/EB family member 3; EB3; EBF3; EBF3-S; RP3
other names :
microtubule-associated protein RP/EB family member 3; Microtubule-associated protein RP/EB family member 3; microtubule-associated protein RP/EB family member 3; APC binding protein; EB1 protein family member 3; end-binding protein 3; microtubule-associated protein, RP/EB family, member 3; EB1 protein family member 3; EBF3; End-binding protein 3; EB3; RP3
products gene name :
MAPRE3
other gene names :
MAPRE3; MAPRE3; EB3; RP3; EBF3; EBF3-S; EBF3; EB3
uniprot entry name :
MARE3_HUMAN
sequence length :
281
sequence :
MGSSHHHHHH SSGLVPRGSH MAVNVYSTSV TSENLSRHDM LAWVNDSLHL NYTKIEQLCS GAAYCQFMDM LFPGCVHLRK VKFQAKLEHE YIHNFKVLQA AFKKMGVDKI IPVEKLVKGK FQDNFEFIQW FKKFFDANYD GKDYNPLLAR QGQDVAPPPN PGDQIFNKSK KLIGTAVPQR TSPTGPKNMQ TSGRLSNVAP PCILRKNPPS ARNGGHETDA QILELNQQLV DLKLTVDGLE KERDFYFSKL RDIELICQEH ESENSPVISG IIGILYATEE GFAPPEDDEI EEHQQEDQDE Y
purity :
> 90 % by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Cell Cycle
products description :
MAPRE1 is a microtubule associated protein that interacts with the colorectal adenomatous polyposis coli tumor suppressor protein and plays important roles in regulating microtubule dynamics, cell polarity, and chromosome stability. This protein is related to MAPRE1 and likewise associates with the microtubule cytoskeleton. MAPRE3 is expressed predominantly in the central nervous system and preferentially associates with APCL, a homolog of the adenomatous polyposis coli tumor suppressor protein. Recombinant human MAPRE3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Berrueta L., et al. (1998) Proc Natl Acad Sci u S A. 95(18):10596-601. Bu W., et al. (2003) J Biol Chem. 278(50):49721-31.
ncbi gi num :
10800412
ncbi acc num :
NP_036458
ncbi gb acc num :
NM_012326.3
ncbi mol weight :
34.1 kDa (301aa)) confirmed by MALDI-TOF
ncbi summary :
The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008]
uniprot summary :
EB3: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. Belongs to the MAPRE family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Microtubule-binding. Chromosomal Location of Human Ortholog: 2p23.3-p23.1. Cellular Component: microtubule cytoskeleton; cytoplasmic microtubule; perinuclear region of cytoplasm; cytoplasm; midbody. Molecular Function: protein binding; microtubule binding. Biological Process: mitosis; positive regulation of cyclin-dependent protein kinase activity; cell division; positive regulation of transcription, DNA-dependent
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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