protein

APOM, 23-188aa, Human, His tag, E Coli

MBS203698

0.05 mg

375 USD

Recombinant Protein

APOM, 23-188aa, Human, His tag, E Coli

APOM

G3a; HSPC336; NG20; Apolipoprotein M Apo M; ApoM; G3A; MGC22400; NG20 like protein; Protein G3a.

apolipoprotein M isoform 1; Apolipoprotein M; apolipoprotein M; NG20-like protein; alternative name: G3a, NG20; protein G3a; apolipoprotein M; Protein G3a

APOM

APOM; APOM; G3a; NG20; apo-M; HSPC336; G3A; NG20; Apo-M; ApoM

APOM_HUMAN

188

MGSSHHHHHH SSGLVPRGSH MCPEHSQLTT LGVDGKEFPE VHLGQWYFIA GAAPTKEELA TFDPVDNIVF NMAAGSAPMQ LHLRATIRMK DGLCVPRKWI YHLTEGSTDL RTEGRPDMKT ELFSSSCPGG IMLNETGQGY QRFLLYNRSP HPPEKCVEEF KSLTSCLDSK AFLLTPRNQE ACELSNN

> 90% by SDS-PAGE

Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT.

1 mg/ml (determined by Bradford assay)

Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.

SDS-PAGE

Antigen Species: Human. Tag: His-tag

Expression System: E Coli

Adhesion & Movement

Apolipoproteins are protein components of plasma lipoproteins. APOM is a member of the lipocalin family of proteins. APOM is exclusively expressed in kidney tubular epithelial cells and liver hepatocytes. APOM is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. It is important for the formation of prebeta-HDL and cholesterol efflux to HDL, and thereby inhibits formation of atherosclerotic lesions. The concentration of APOM in plasma strongly correlates with total cholesterol. Low concentrations of APOM in plasma are associated with diabetes. Recombinant human APOM protein was expressed in E.coli and purified by using conventional chromatography techniques.

Jiang J., et al. (2008) Lipids Health Dis. 7:25. Duan J., et al. (2001) FEBS Lett. 499(1-2):127-32.

22091452

NP_061974

NM_019101.2

20.9 kDa (187aa), confirmed by MALDI-TOF.

The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]

APOM: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. Plasma protein. Expressed in liver and kidney. Belongs to the calycin superfamily. Lipocalin family. Highly divergent. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 6p21.33. Cellular Component: integral to plasma membrane. Molecular Function: lipid transporter activity; antioxidant activity; phospholipid binding. Biological Process: cholesterol homeostasis; reverse cholesterol transport; response to glucose stimulus; lipoprotein metabolic process; cholesterol efflux

0.05 mg

375 USD

0.25 mg

925