HRP-Linked Polyclonal Antibody to Interleukin 2 (IL2) | MyBioSource MBS2036850 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

HRP-Linked Polyclonal Antibody to Interleukin 2 (IL2)

catalog :

MBS2036850

quantity :

0.1 mg

price :

295 USD

clonality :

polyclonal

host :

rabbit

conjugate :

HRP

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2036850

products type :

Antibody

products full name :

HRP-Linked Polyclonal Antibody to Interleukin 2 (IL2)

products short name :

[Interleukin 2 (IL2)]

products name syn :

[TCGF; Lymphokine; T-Cell Growth Factor; Aldesleukin]

other names :

[interleukin 2; Interleukin-2; interleukin-2; interleukin 2; T-cell growth factor; TCGF; INN: Aldesleukin]

products gene name :

[IL2]

other gene names :

[IL2; IL2; IL-2; TCGF; lymphokine; IL-2; TCGF]

clonality :

Polyclonal

host :

Rabbit

reactivity :

Bovine (Cattle)

purity :

Antigen-specific Affinity Chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

200ug/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; IHC; ICC; IP

app notes :

Western blotting: 0.5-2µg/mL. Immunohistochemistry: 5-20µg/mL. Immunocytochemistry: 5-20µg/mL. Optimal working dilutions must be determined by end user

other info1 :

Source: Antibody labeling. Label: HRP. Traits: Liquid. Immunogen: Recombinant IL2 (Ala21~Thr155) expressed in E.coli.

other info2 :

Unconjugated Antibody: The unconjugated antibody version of this item is also available as catalog #MBS2027352

ncbi gi num :

5729676

ncbi acc num :

AAD48509.1

ncbi pathways :

ARMS-mediated Activation Pathway (1269471); Allograft Rejection Pathway (920963); Allograft Rejection Pathway (83123); Allograft Rejection Pathway (535); Aryl Hydrocarbon Receptor Pathway (1458288); Autoimmune Thyroid Disease Pathway (83121); Autoimmune Thyroid Disease Pathway (533); Axon Guidance Pathway (1270303); Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993); Calcium Signaling In The CD4+ TCR Pathway (137941)

ncbi summary :

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]

uniprot summary :

IL2: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells. A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. Belongs to the IL-2 family. Protein type: Cytokine; Oncoprotein; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q27. Cellular Component: extracellular region; extracellular space. Molecular Function: cytokine activity; growth factor activity; interleukin-2 receptor binding; kinase activator activity; Ras guanyl-nucleotide exchange factor activity. Biological Process: cell adhesion; cell-cell signaling; immune response; MAPKKK cascade; natural killer cell activation; negative regulation of apoptosis; negative regulation of B cell apoptosis; positive regulation of activated T cell proliferation; positive regulation of B cell proliferation; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of inflammatory response; positive regulation of interleukin-17 production; positive regulation of tissue remodeling; positive regulation of tyrosine phosphorylation of Stat5 protein; T cell differentiation

size1 :

0.1 mg

price1 :

295 USD

size2 :

0.2 mg

price2 :

465

size3 :

1 mg

price3 :

1110

more info or order :

MyBioSource product webpage