catalog number :
MBS203673
products type :
Recombinant Protein
products full name :
ADAT2, 1-191aa, Human, His tag, E Coli
products short name :
ADAT2
products name syn :
tRNA-specific adenosine deaminase 2; DEADC1; TAD2
other names :
tRNA-specific adenosine deaminase 2 isoform a; tRNA-specific adenosine deaminase 2; tRNA-specific adenosine deaminase 2; adenosine deaminase, tRNA-specific 2, TAD2 homolog; deaminase domain containing 1; deaminase domain-containing protein 1; tRNA-specific adenosine deaminase 2 homolog; tRNA-specific adenosine-34 deaminase subunit ADAT2; adenosine deaminase, tRNA-specific 2; Deaminase domain-containing protein 1; tRNA-specific adenosine-34 deaminase subunit ADAT2
products gene name :
ADAT2
other gene names :
ADAT2; ADAT2; TAD2; DEADC1; dJ20N2; dJ20N2.1; DEADC1
uniprot entry name :
ADAT2_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MEAKAAPKPA ASGACSVSAE ETEKWMEEAM HMAKEALENT EVPVGCLMVY NNEVVGKGRN EVNQTKNATR HAEMVAIDQV LDWCRQSGKS PSEVFEHTVL YVTVEPCIMC AAALRLMKIP LVVYGCQNER FGGCGSVLNI ASADLPNTGR PFQCIPGYRA EEAVEMLKTF YKQENPNAPK SKVRKKECQK S
purity :
> 90% by SDS - PAGE
form :
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 50mM NaCl
concentration :
0.5mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Enzymes & Proteases
products description :
Adenosine deaminase (ADA), also known as ADAT2 is an enzyme involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. Also, ADAT2 is thought to participate in the deamination of adenosine-34 to inosine in many tRNAs. Belonging to the cytidine and deoxycytidylate deaminase protein family, ADAT2 employs zinc as a cofactor. ADAT2 is a 191 amino acid protein that exists as two isoforms produced by alternative splicing events. Recombinant human ADAT2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Persico AM, et al. (2000) Am. J. Med. Genet. 96 (6): 784-90. Kimura, K., et al. (2006) Genome Res. 16: 55-65.
ncbi gb acc num :
NM_182503.2
ncbi mol weight :
23.2kDa (211aa), confirmed by MALDI-TOF