product summary
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company name :
MyBioSource
product type :
protein
product name :
WDR5, 1-334aa, Human, His tag, E Coli
catalog :
MBS203657
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203657
products type :
Recombinant Protein
products full name :
WDR5, 1-334aa, Human, His tag, E Coli
products short name :
WDR5
products name syn :
BIG-3; SWD3; WD repeat-containing protein 5; BIG 3; WDR 5; WDR-5
other names :
WD repeat-containing protein 5; WD repeat-containing protein 5; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog; WD-repeat protein 5; cilia and flagella associated protein 89; WD repeat domain 5; BMP2-induced 3-kb gene protein
products gene name :
WDR5
other gene names :
WDR5; WDR5; SWD3; BIG-3; CFAP89; BIG3
uniprot entry name :
WDR5_HUMAN
sequence length :
334
sequence :
MGSSHHHHHH SSGLVPRGSH MATEEKKPET EAARAQPTPS SSATQSKPTP VKPNYALKFT LAGHTKAVSS VKFSPNGEWL ASSSADKLIK IWGAYDGKFE KTISGHKLGI SDVAWSSDSN LLVSASDDKT LKIWDVSSGK CLKTLKGHSN YVFCCNFNPQ SNLIVSGSFD ESVRIWDVKT GKCLKTLPAH SDPVSAVHFN RDGSLIVSSS YDGLCRIWDT ASGQCLKTLI DDDNPPVSFV KFSPNGKYIL AATLDNTLKL WDYSKGKCLK TYTGHKNEKY CIFANFSVTG GKWIVSGSED NLVYIWNLQT KEIVQKLQGH TDVVISTACH PTENIIASAA LENDKTIKLW KSDC
purity :
> 95 % by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Transcription & Translation
products description :
WDR5, also designated BMP-2-induced gene 3 kb or BIG-3, belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. This protein is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. WDR5 may play a role in its function of accelerating osteoblast differentiation. Recombinant human WDR5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Yokoyama., et al. (2004) Mol Cell Biol. 24(13):5639-49. Gori F., et al. (2001) J Biol Chem. 276(49):46515-22.
ncbi gi num :
16554629
ncbi acc num :
NP_438172
ncbi gb acc num :
NM_052821.3
ncbi mol weight :
38.8 kDa (354aa), confirmed by MALDI-TOF
ncbi pathways :
Chromatin Modifying Enzymes Pathway 1127682!!Chromatin Organization Pathway 1127681!!Circadian Rhythm Pathway 137978!!HATs Acetylate Histones Pathway 1127683!!PKMTs Methylate Histone Lysines Pathway 1127686!!RMTs Methylate Histone Arginines Pathway 1127687
ncbi summary :
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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