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company name :
MyBioSource
product type :
protein
product name :
TALDO1, 1-337aa, Human, His tag, E Coli
catalog :
MBS203637
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203637
products type :
Recombinant Protein
products full name :
TALDO1, 1-337aa, Human, His tag, E Coli
products short name :
TALDO1
products name syn :
TAL; TAL-H; TALDOR; TALH; TALDO1; Transaldolase 1
other names :
transaldolase; Transaldolase; transaldolase; dihydroxyacetone transferase; glycerone transferase; transaldolase 1
products gene name :
TALDO1
other gene names :
TALDO1; TALDO1; TAL; TALH; TAL-H; TALDOR; TAL; TALDO; TALDOR
uniprot entry name :
TALDO_HUMAN
sequence length :
337
sequence :
MGSSHHHHHH SSGLVPRGSH MSSSPVKRQR MESALDQLKQ FTTVVADTGD FHAIDEYKPQ DATTNPSLIL AAAQMPAYQE LVEEAIAYGR KLGGSQEDQI KNAIDKLFVL FGAEILKKIP GRVSTEVDAR LSFDKDAMVA RARRLIELYK EAGISKDRIL IKLSSTWEGI QAGKELEEQH GIHCNMTLLF SFAQAVACAE AGVTLISPFV GRILDWHVAN TDKKSYEPLE DPGVKSVTKI YNYYKKFSYK TIVMGASFRN TGEIKALAGC DFLTISPKLL GELLQDNAKL VPVLSAKAAQ ASDLEKIHLD EKSFRWLHNE DQMAVEKLSD GIRKFAADAV KLERMLTERM FNAENGK
purity :
> 90% by SDS - PAGE
form :
Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Cancer
products description :
TALDO1 is a key enzyme of the non-oxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This protein transfers a dihydroxyacetone group from donor compounds (fructose 6-phosphate or sedoheptulose 7-phosphate) to aldehyde acceptor compounds. It is expressed at selectively high levels in oligodendrocytes of the brain. Deficiency of TALDO1 causes accumulation of erythritol, D-arabitol, and ribitol. Recombinant human TALDO1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
products references :
Sprenger GA., et al. (2009) Int J Biochem Cell Biol. 41(7):1482-94. Saudubray JM., et al (2006) J Pediatr. 149(5):713-7.
ncbi gi num :
5803187
ncbi acc num :
NP_006746
ncbi gb acc num :
NM_006755.1
ncbi mol weight :
39.7 kDa(357aa), confirmed by MALDI-TOF
ncbi pathways :
Biosynthesis Of Amino Acids Pathway 790012!!Biosynthesis Of Amino Acids Pathway 795174!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Disease Pathway 530764!!Glycogen Storage Diseases Pathway 1127581!!Insulin Effects Increased Synthesis Of Xylulose-5-Phosphate Pathway 106101!!Integration Of Energy Metabolism Pathway 106096!!Metabolic Pathways 132956!!Metabolism Pathway 477135
ncbi summary :
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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