catalog number :
MBS203616
products type :
Recombinant Protein
products full name :
CRYZL1, 1-349aa, Human, His tag, E Coli
products short name :
CRYZL1
products name syn :
4P11; QOH-1; Quinone oxidoreductase-like protein 1 QOH 1; QOH1; Quinone oxidoreductase like 1; Quinone reductase like 1; Zeta crystallin homolog
other names :
quinone oxidoreductase-like protein 1; Quinone oxidoreductase-like protein 1; quinone oxidoreductase-like protein 1; protein 4P11; quinone oxidoreductase homolog 1; quinone reductase-like 1; zeta-crystallin homolog; crystallin, zeta (quinone reductase)-like 1; Protein 4P11; Quinone oxidoreductase homolog 1; QOH-1; Zeta-crystallin homolog
products gene name :
CRYZL1
other gene names :
CRYZL1; CRYZL1; 4P11; QOH-1; 4P11; QOH-1
uniprot entry name :
QORL1_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MKGLYFQQSS TDEEITFVFQ EKEDLPVTED NFVKLQVKAC ALSQINTKLL AEMKMKKDLF PVGREIAGIV LDVGSKVSFF QPDDEVVGIL PLDSEDPGLC EVVRVHEHYL VHKPEKVTWT EAAGSIRDGV RAYTALHYLS HLSPGKSVLI MDGASAFGTI AIQLAHHRGA KVISTACSLE DKQCLERFRP PIARVIDVSN GKVHVAESCL EETGGLGVDI VLDAGVRLYS KDDEPAVKLQ LLPHKHDIIT LLGVGGHWVT TEENLQLDPP DSHCLFLKGA TLAFLNDEVW NLSNVQQGKY LCILKDVMEK LSTGVFRPQL DEPIPLYEAK VSMEAVQKNQ GRKKQVVQF
purity :
> 95% by SDS - PAGE
form :
Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 2mM DTT, 0.1M NaCl, 20% glycerol
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Redox Proteins
products description :
CRYZL1, also known as quinone oxidoreductase, is a protein that has sequence similarity to zeta crystalline. This Protein is present at low levels in human lens tissue. It has NADPH-dependent quinone reductase activity distinct from other known quinone reductases, and may play a role as a pH response element-binding protein. CRYZL1 is expressed at various levels in heart, brain, skeletal muscle, kidney, pancreas, liver and lung. Recombinant human CRYZL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Cai SF., et al. (2009) Molecules. 14(8):2935-46. Tauraite D., et al. (2009) Chem Phys Lipids. 159(1):45-50.
ncbi gb acc num :
NM_145858.2
ncbi mol weight :
40.8 kDa (369aa), confirmed by MALDI-TOF
ncbi summary :
This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]
uniprot summary :
CRYZL1: a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]. Protein type: EC 1.-.-.-; Oxidoreductase. Chromosomal Location of Human Ortholog: 21q21.3. Cellular Component: cytosol. Molecular Function: zinc ion binding; NADPH:quinone reductase activity; NADP binding