product summary
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company name :
MyBioSource
product type :
protein
product name :
GDF-15, 195-308aa, Human, His-tag, E Coli
catalog :
MBS203555
quantity :
0.1 mg
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203555
products type :
Recombinant Protein
products full name :
GDF-15, 195-308aa, Human, His-tag, E Coli
products short name :
GDF-15
products name syn :
GDF15; GDF-15; MIC-1; MIC1; NAG-1; PDF; PLAB; PTGFB; Growth differentiation factor 15 NSAID regulated protein 1; Placental TGF beta; GDF 15; Growth/differentiation factor 15; Macrophage inhibitory cytokine 1; MIC 1; NAG 1; NAG1; NRG 1; NRG1; NSAID; NSAID (nonsteroidal anti inflammatory drug) activated protein 1; Placental bone morphogenetic protein; Placental bone morphogenic protein; Prostate differentiation factor; PTGF beta; PTGFB.
other names :
growth/differentiation factor 15; Growth/differentiation factor 15; growth/differentiation factor 15; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PTGF-beta; macrophage inhibitory cytokine 1; placental TGF-beta; placental bone morphogenetic protein; prostate differentiation factor; growth differentiation factor 15; Macrophage inhibitory cytokine 1; MIC-1; NSAID-activated gene 1 protein; NAG-1; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor
products gene name :
GDF-15
other gene names :
GDF15; GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; MIC1; PDF; PLAB; PTGFB; GDF-15; MIC-1; NAG-1; NRG-1
uniprot entry name :
GDF15_HUMAN
sequence length :
308
sequence :
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMARA RNGDHCPLGP GRCCRLHTVR ASLEDLGWAD WVLSPREVQV TMCIGACPSQ FRAANMHAQI KTSLHRLKPD TVPAPCCVPA SYNPMVLIQK TDTGVSLQTY DDLLAKDCHC I
purity :
> 95% by SDS - PAGE
form :
Liquid. In 10mM Sodium Citrate (pH3.5) containing 10% glycerol
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli. Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)
products categories :
Growth factors
products description :
Growth differentiation factor 15 (GDF-15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. This protein is most abundant in the liver, with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF-15 was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
products references :
Paralkar V.M, et al. (1998) J Biol Chem. 273:13760-13767. Hsiao E, Koniaris L., et al. (2000) Mol Cell Biol 20(10):3742-51.
ncbi gi num :
153792495
ncbi acc num :
NP_004855
ncbi gb acc num :
NM_004864.2
ncbi mol weight :
16.7 kDa (151aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
ncbi pathways :
Direct P53 Effectors Pathway 137939
ncbi summary :
Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM, Oct 2009]
size :
0.1 mg
price :
510 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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