product summary
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company name :
MyBioSource
product type :
protein
product name :
SHH, 25-198aa, Mouse, His-tag, Recombinant, E Coli
catalog :
MBS203523
quantity :
0.1 mg
price :
285 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203523
products type :
Recombinant Protein
products full name :
SHH, 25-198aa, Mouse, His-tag, Recombinant, E Coli
products short name :
SHH
products name syn :
Dsh; Hhg1; Hx; Hx13; Sonic hedgehog protein HHG 1; HHG1; HLP 3; HLP3; Holoprosencephaly 3; HPE 3; HPE3; MCOPCB5; SHH; SMMC I; SMMCI; Sonic Hedgehog (Drosophila) homolog; sonic hedgehog homolog (Drosophila); Sonic hedgehog homolog; TPT; TPTPS.
other names :
sonic hedgehog protein; Sonic hedgehog protein; sonic hedgehog protein; HHG-1; hemimelic extra toes; short digits; sonic hedgehog; HHG-1Cleaved into the following 2 chains:Sonic hedgehog protein N-productAlternative name(s):Sonic hedgehog protein 19 kDa product
products gene name :
SHH
other gene names :
Shh; Shh; Hx; Dsh; Hhg1; Hxl3; M100081; 9530036O11Rik; Hhg1; SHH
uniprot entry name :
SHH_MOUSE
sequence length :
437
sequence :
MCGPGRGFGK RRHPKKLTPL AYKQFIPNVA EKTLGASGRY EGKITRNSER FKELTPNYNP DIIFKDEENT GADRLMTQRC KDKLNALAIS VMNQWPGVKL RVTEGWDEDG HHSEESLHYE GRAVDITTSD RDRSKYGMLA RLAVEAGFDW VYYESKAHIH CSVKAENSVA AKSGGLEHHH HHH
purity :
> 95% by SDS-PAGE
form :
Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT.
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli. Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)
products categories :
Development
products description :
SHH is one of three proteins in the mammalian signaling pathway family called hedgehog, the others being desert hedgehog (DHH) and Indian hedgehog (IHH). This protien is the best studied ligand of the hedgehog signaling pathway. It plays a key role in regulating vertebrate organogenesis. SHH contain amino-terminal signal peptides and apparently function as secreted proteins involved in the mediation of various cell-cell interactions. Recombinant mouse SHH protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Bak M., et al. (2004) Brain Res Mol Brain Res. 126(2):207-11. Dassule HR., et al. (2000) Development. 127(22):4775-85.
ncbi gi num :
21617861
ncbi acc num :
NP_033196
ncbi gb acc num :
NM_009170.3
ncbi mol weight :
20.8 kDa (183aa), confirmed by MALDI-TOF
ncbi pathways :
Activation Of SMO Pathway 1110597!!Basal Cell Carcinoma Pathway 83306!!Basal Cell Carcinoma Pathway 525!!Class B/2 (Secretin Family Receptors) Pathway 1110524!!Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway 1111486!!Disease Pathway 1111319!!Dopminergic Neurogenesis Pathway 198342!!GPCR Ligand Binding Pathway 1110498!!Heart Development Pathway 672437!!Hedgehog 'on' State Pathway 1110595
size :
0.1 mg
price :
285 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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