product summary
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company name :
MyBioSource
product type :
protein
product name :
HMGN1, 1-100aa, Human, His tag, E Coli
catalog :
MBS203453
quantity :
0.05 mg
price :
375 USD
more info or order :
image
image 1 :
product information
catalog number :
MBS203453
products type :
Recombinant Protein
products full name :
HMGN1, 1-100aa, Human, His tag, E Coli
products short name :
[HMGN1]
products name syn :
[Non-histone chromosomal protein HMG-14; HMG14; GC104230; Non-histone chromosomal protein HMG-14 FLJ27265; FLJ31471; High mobility group (nonhistone chromosomal) protein 14; High mobility group nucleosome binding 1; High mobility group nucleosome binding domain 1; High mobility group nucleosome binding domain containing protein 1; High mobility group protein 14; HMG 14 HMGN 1; HMGN1; MGC104230; MGC117425; Nonhistone chromosomal protein HMG 14; Nonhistone chromosomal protein HMG14.]
other names :
[non-histone chromosomal protein HMG-14; Non-histone chromosomal protein HMG-14; non-histone chromosomal protein HMG-14; high mobility group nucleosome binding domain 1; High mobility group nucleosome-binding domain-containing protein 1]
products gene name :
[HMGN1]
other gene names :
[HMGN1; HMGN1; HMG14; HMG14]
host :
E Coli
sequence length :
100
sequence :
MPKRKVSSAE GAAKEEPKRR SARLSAKPPA KVEAKPKKAA AKDKSSDKKV QTKGKRGAKG KQAEVANQET KEDLPAENGE TKTEESPASD EAGEKEAKSD LEHHHHHH
purity :
> 95% by SDS-PAGE
form :
Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT, 0.1mM PMSF
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-Page
other info1 :
Antigen Species: Human. Tag Information: His-tag
products categories :
Transcription & Translation
products description :
HMGN1, also known as non-histone chromosomal protein HMG-14, belongs to the HMGN family. Chromosomal protein HMGN1 binds to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. This protein may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Recombinant human HMGN1 protein was expressed in E Coli and purified by using conventional chromatography techniques.
products references :
Landsman D. et al, (1989) J Biol Chem. 264 (6):3421-7
ncbi gi num :
48255933
ncbi acc num :
NP_004956
ncbi gb acc num :
NM_004965.6
uniprot acc num :
P05114
ncbi mol weight :
11.7 kDa (108aa), confirmed by MALDI-TOF.
ncbi pathways :
ATM Signaling Network In Development And Disease Pathway (1458202); DNA Repair Pathway (1270350); Dual Incision In TC-NER Pathway (1309119); Formation Of TC-NER Pre-Incision Complex Pathway (1309118); Gap-filling DNA Repair Synthesis And Ligation In TC-NER Pathway (1309120); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865); Nucleotide Excision Repair Pathway (1309111); Transcription-Coupled Nucleotide Excision Repair (TC-NER) Pathway (1309117); P38 MAPK Signaling Pathway (198893)
ncbi summary :
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes. [provided by RefSeq, Aug 2011]
uniprot summary :
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 ().
size1 :
0.05 mg
price1 :
375 USD
size2 :
0.25 mg
price2 :
925
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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