catalog number :
MBS2034499
products type :
Recombinant Protein
products full name :
Recombinant Nucleobindin 1 (NUCB1)
products short name :
[Nucleobindin 1]
products name syn :
[NUC; CALNUC]
other names :
[Nucleobindin 1; Nucleobindin-1; nucleobindin-1; nucleobindin 1; CALNUC]
products gene name :
[NUCB1]
other gene names :
[NUCB1; NUCB1; NUC; CALNUC; NUC]
uniprot entry name :
NUCB1_HUMAN
concentration :
Original Concentration: 200 ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control; Immunogen; SDS-PAGE; Western blot (WB). (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
Sequence
image2 heading :
SDS-Page
other info1 :
Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Glu37~Leu461. Tags: N-terminal His Tag. Subcellular Location: Membrane. Traits: Freeze-dried powder. Buffer: 100mMNaHCO3, 500mMNaCl, pH8.3, containing 0.01% SKL, 5% Trehalose.
other info2 :
Predicted isoelectric point: 5.1. Usage: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex.
ncbi acc num :
AAH02356.1
ncbi mol weight :
Predicted Molecular Mass: 53.8kDa. Accurate Molecular Mass: 54kDa as determined by SDS-PAGE reducing conditions.
ncbi summary :
This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. [provided by RefSeq, Jun 2010]
uniprot summary :
NUCB1: Major calcium-binding protein of the Golgi. May have a role in calcium homeostasis. Belongs to the nucleobindin family. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 19q13.33. Cellular Component: cis-Golgi network; early endosome; ER-Golgi intermediate compartment; extracellular space; Golgi apparatus; Golgi-associated vesicle; membrane; microtubule cytoskeleton; nucleus; rough endoplasmic reticulum; trans-Golgi network. Molecular Function: calcium ion binding; DNA binding; G-protein alpha-subunit binding; protein binding