product summary
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company name :
MyBioSource
product type :
protein
product name :
ATOX1, 1-68aa, Human, His tag, E Coli
catalog :
MBS203443
quantity :
0.1 mg
price :
285 USD
more info or order :
product information
catalog number :
MBS203443
products type :
Recombinant Protein
products full name :
ATOX1, 1-68aa, Human, His tag, E Coli
products short name :
ATOX1
products name syn :
Antioxidant protein 1; ATX1; HAH1; Copper transport protein ATOX1 ATX1; Copper transport protein; Metal transport protein.
other names :
copper transport protein ATOX1; Copper transport protein ATOX1; copper transport protein ATOX1; ATX1 antioxidant protein 1 homolog; metal transport protein ATX1; antioxidant 1 copper chaperone; Metal transport protein ATX1
products gene name :
ATOX1
other gene names :
ATOX1; ATOX1; ATX1; HAH1; HAH1
uniprot entry name :
ATOX1_HUMAN
sequence length :
68
sequence :
MGSSHHHHHH SSGLVPRGSH MPKHEFSVDM TCGGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LLATLKKTGK TVSYLGLE
purity :
> 95% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Heat Shock Proteins
products description :
Copper transport protein ATOX1, also known as HAH1, a metal transport protein that belongs to the ATX1 family. ATOX1 is involved in cellular antioxidant defense and can bind and deliver cytosolic copper to the copper ATPase proteins. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. Recombinant human ATOX1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Klomp LW., et al. (1997) J Biol Chem. 272(14):9221-6. Hamzal I., et al. (1999) Proc Natl Acad Sci uSA. 96(23):13363-8.
ncbi gi num :
4757804
ncbi acc num :
NP_004036
ncbi gb acc num :
NM_004045.3
ncbi mol weight :
9.5 kDa (88aa), confirmed by MALDI-TOF.
ncbi pathways :
Cellular Responses To Stress Pathway 645258!!Detoxification Of Reactive Oxygen Species Pathway 1127552!!Mineral Absorption Pathway 212237!!Mineral Absorption Pathway 212220
ncbi summary :
This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
285 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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