product summary
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company name :
MyBioSource
product type :
protein
product name :
LYPLA1, 1-230aa, Mouse, His tag, E Coli
catalog :
MBS203417
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203417
products type :
Recombinant Protein
products full name :
LYPLA1, 1-230aa, Mouse, His tag, E Coli
products short name :
LYPLA1
products name syn :
Acyl-protein thioesterase 1; lysophospholipase 1; Pla1a; APT-1; LysoPLA I; LPL-I; APT1
other names :
acyl-protein thioesterase 1; Acyl-protein thioesterase 1; acyl-protein thioesterase 1; APT-1; LPL-I; lysoPLA I; lysophopholipase 1; lysophospholipase I; phospholipase 1a; lysophospholipase 1; Lysophospholipase 1; Lysophospholipase I; LPL-I; LysoPLA I
products gene name :
LYPLA1
other gene names :
Lypla1; Lypla1; Pla1a; Apt1; Pla1a; APT-1; LPL-I; LysoPLA I
uniprot entry name :
LYPA1_MOUSE
sequence length :
230
sequence :
MGSSHHHHHH SSGLVPRGSH MCGNNMSAPM PAVVPAARKA TAAVIFLHGL GDTGHGWAEA FAGIKSPHIK YICPHAPVMP VTLNMNMAMP SWFDIVGLSP DSQEDESGIK QAAETVKALI DQEVKNGIPS NRIILGGFSQ GGALSLYTAL TTQQKLAGVT ALSCWLPLRA SFSQGPINSA NRDISVLQCH GDCDPLVPLM FGSLTVERLK ALINPANVTF KIYEGMMHSS CQQEMMDVKH FIDKLLPPID
purity :
> 90% by SDS - PAGE
form :
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl,1mM DTT
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Mouse. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Metabolism
products description :
LYPLA1 is lysophospholipase that acts on biological membranes to regulate the multifunctional lysophospholipids. This protein hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS and also has depalmitoylating activity. Recombinant mouse LYPLA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
products references :
Schaloske R.H., et al. (2006) Biochim Biophys Acta. 1761:1246-1259. Hiraoka M., et al. (2002) J. Biol. Chem 277:10090-10099.
ncbi gi num :
6678760
ncbi acc num :
NP_032892
ncbi gb acc num :
NM_008866.2
ncbi mol weight :
26.8 kDa (250aa), confirmed by MALDI-TOF
ncbi pathways :
Choline Metabolism In Cancer Pathway (1060314); Choline Metabolism In Cancer Pathway (1084232); Glycerophospholipid Metabolism Pathway (83188); Glycerophospholipid Metabolism Pathway (364); Metabolism Pathway (1110796); Metabolism Of Nitric Oxide Pathway (1110942); ENOS Activation Pathway (1110944); ENOS Activation And Regulation Pathway (1110943)
uniprot summary :
LYPLA1: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity. Belongs to the AB hydrolase 2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.1.2.-; Phospholipase; Lipid Metabolism - glycerophospholipid. Cellular Component: mitochondrion; cytoplasm; cytosol. Molecular Function: acyl-CoA hydrolase activity; hydrolase activity; palmitoyl-(protein) hydrolase activity; CoA hydrolase activity; lysophospholipase activity. Biological Process: negative regulation of Golgi to plasma membrane protein transport; lipid metabolic process; fatty acid metabolic process; protein depalmitoylation
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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