catalog number :
MBS2034063
products full name :
Polyclonal Antibody to Cathepsin W (CTSW)
products short name :
[Cathepsin W]
products name syn :
[CTS-W; LYPN; Lymphopain]
other names :
[cathepsin W preproprotein; Cathepsin W; cathepsin W; cathepsin W; Lymphopain]
products gene name :
[CTSW]
other gene names :
[Ctsw; Ctsw; lymphopain]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)
app notes :
Western blotting: 0.5-2ug/mL;1:500-2000. Immunohistochemistry: 5-20ug/mL;1:50-200. Immunocytochemistry: 5-20ug/mL;1:50-200. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation
other info2 :
Immunogen: Recombinant CTSW (Asp22~Pro371) expressed in E.coli
ncbi acc num :
NP_034115.2
ncbi gb acc num :
NM_009985.5
ncbi pathways :
Lysosome Pathway (99272); Lysosome Pathway (96865)
ncbi summary :
This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate a mature protein product. Expression of the encoded protein is upregulated following lymphocyte activation. Data from a human cell line suggests that the encoded enzyme may be important for viral entry into host cells. [provided by RefSeq, Aug 2015]
uniprot summary :
CTSW: May have a specific function in the mechanism or regulation of T-cell cytolytic activity. Belongs to the peptidase C1 family. Protein type: EC 3.4.22.-; Protease. Chromosomal Location of Human Ortholog: 19 19 A. Cellular Component: extracellular space; lysosome; membrane. Molecular Function: cysteine-type endopeptidase activity; cysteine-type peptidase activity; hydrolase activity; peptidase activity. Biological Process: proteolysis; proteolysis involved in cellular protein catabolic process