catalog number :
MBS2033915
products full name :
Polyclonal Antibody to Olfactomedin 3 (OLFM3)
products short name :
[Olfactomedin 3]
products name syn :
[NOE3; NOELIN3; NOELIN3_V1; NOELIN3_V2; NOELIN3_V3; NOELIN3_V4; NOELIN3_V5; NOELIN3_V6; Optimedin]
other names :
[olfactomedin-like protein 3; Olfactomedin-like protein 3; olfactomedin-like protein 3; olfactomedin-like 3]
products gene name :
[OLFM3]
other gene names :
[Olfml3; Olfml3; ONT3; mONT3; AI115209; AW550633; HNOEL-iso; 2810002E22Rik]
specificity :
The antibody is a Rabbit polyclonal antibody raised against OLFM3. It has been selected for its ability to recognize OLFM3 in immunohistochemical staining and western blotting.
purity :
Antigen-specific affinity chromatography followed by Protein A affinity
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP
app notes :
Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-20ug/mL. Immunocytochemistry: 5-20ug/mL. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant OLFM3 (His245~Val406) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2067587
ncbi acc num :
NP_598620.2
ncbi gb acc num :
NM_133859.2
ncbi mol weight :
45,746 Da
uniprot summary :
OLFML3: Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation. May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes. Belongs to the OLFML3 family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3 3 F2.2