Polyclonal Antibody to Alanine Glyoxylate Aminotransferase 2 (AGXT2) | MyBioSource MBS2033904 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Alanine Glyoxylate Aminotransferase 2 (AGXT2)

catalog :

MBS2033904

quantity :

0.01 mg

price :

140 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2033904

products type :

Antibody

products full name :

Polyclonal Antibody to Alanine Glyoxylate Aminotransferase 2 (AGXT2)

products short name :

Alanine Glyoxylate Aminotransferase 2

products name syn :

AGT2; Beta-Alanine-Pyruvate Aminotransferase; (R)-3-amino-2-methylpropionate--pyruvate transaminase

other names :

alanine-glyoxylate aminotransferase 2; Alanine--glyoxylate aminotransferase 2, mitochondrial; alanine--glyoxylate aminotransferase 2, mitochondrial; alanine--glyoxylate aminotransferase 2; (R)-3-amino-2-methylpropionate--pyruvate transaminase (EC:2.6.1.40); Beta-ALAAT II; Beta-alanine-pyruvate aminotransferase; D-AIBAT

products gene name :

AGXT2

other gene names :

AGXT2; AGXT2; AGT2; DAIBAT; AGT2; AGT 2

uniprot entry name :

AGT2_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Rat

sequence length :

514

specificity :

The antibody is a rabbit polyclonal antibody raised against AGXT2. It has been selected for its ability to recognize AGXT2 in immunohistochemical staining and western blotting.

purity :

Antigen-specific Affinity Chromatography.

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

200ug/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM

app notes :

Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.

other info1 :

Source: Polyclonal antibody preparation. Traits: Liquid

other info2 :

Immunogen: Recombinant AGXT2 (Met225~Lys512) expressed in E.coli.

ncbi gi num :

12406973

ncbi acc num :

CAC24841.1

uniprot acc num :

Q9BYV1

ncbi pathways :

Alanine, Aspartate And Glutamate Metabolism Pathway (101142); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Cysteine And Methionine Metabolism Pathway (104488); Cysteine And Methionine Metabolism Pathway (103421); Glycine, Serine And Threonine Metabolism Pathway (82949); Glycine, Serine And Threonine Metabolism Pathway (313); Glyoxylate Metabolism And Glycine Degradation Pathway (1270180); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Amino Acids And Derivatives Pathway (1270158)

ncbi summary :

The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

uniprot summary :

AGXT2: is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. [provided by RefSeq, Dec 2008]. Protein type: Transferase; EC 2.6.1.44; EC 2.6.1.40; Amino Acid Metabolism - alanine, aspartate and glutamate; Mitochondrial. Chromosomal Location of Human Ortholog: 5p13. Cellular Component: mitochondrial matrix; mitochondrion. Molecular Function: (R)-3-amino-2-methylpropionate-pyruvate transaminase activity; alanine-glyoxylate transaminase activity; beta-alanine-pyruvate transaminase activity; identical protein binding; pyridoxal phosphate binding. Biological Process: glycine biosynthetic process, by transamination of glyoxylate; glyoxylate catabolic process; glyoxylate metabolic process; L-alanine catabolic process, by transamination; nucleobase, nucleoside and nucleotide metabolic process; positive regulation of nitric oxide biosynthetic process; pyrimidine base metabolic process; pyrimidine nucleoside catabolic process

size1 :

0.01 mg

price1 :

140 USD

size2 :

0.05 mg

price2 :

250

size3 :

0.1 mg

price3 :

345

more info or order :

MyBioSource product webpage