product summary
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company name :
MyBioSource
product type :
protein
product name :
Profilin 1, 1-140aa, Human, Recombinant, E Coli
catalog :
MBS203377
quantity :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203377
products type :
Recombinant Protein
products full name :
Profilin 1, 1-140aa, Human, Recombinant, E Coli
products short name :
Profilin 1
products name syn :
PFN1; Actin binding protein; Pfn; PFN 1; Profilin I; Profilin1; ProfilinI.
other names :
profilin-1; Profilin-1; profilin-1; epididymis tissue protein Li 184a; profilin I; profilin 1; Epididymis tissue protein Li 184a; Profilin I
other gene names :
PFN1; PFN1; ALS18
uniprot entry name :
PROF1_HUMAN
sequence length :
140
sequence :
MAGWNAYIDN LMADGTCQDA AIVGYKDSPS VWAAVPGKTF VNITPAEVGV LVGKDRSSFY VNGLTLGGQK CSVIRDSLLQ DGEFSMDLRT KSTGGAPTFN VTVTKTDKTL VLLMGKEGVH GGLINKKCYE MASHLRRSQY
purity :
> 95% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol
concentration :
1.0 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli. Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)
products categories :
Cytoskeleton
products description :
Profilin1 is a ubiquitous actin monomer-binding protein belonging to the profilin family. This protein significantly enhances skin wound healing in-vitro and in-vivo that may be mediated by purinergic receptors. It is also active in endothelial cell migration and vessel sprouting. It is thought to regulate actin polymerization in response to extracellular signals. Recombinant Profilin1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Kwiatkowski DJ, et al. (1988) J. Biol. Chem. 263(12): 5910-5. Harbeck B., et al. (2000) J. Biol. Chem. 275(40): 30817-25.
ncbi gi num :
4826898
ncbi acc num :
NP_005013
ncbi gb acc num :
NM_005022.3
ncbi mol weight :
15.0 kDa (140aa), confirmed by MALDI-TOF.
ncbi pathways :
Axon Guidance Pathway 105688!!Developmental Biology Pathway 477129!!G13 Signaling Pathway 198800!!Hemostasis Pathway 106028!!PCP/CE Pathway 1127528!!Platelet Activation, Signaling And Aggregation Pathway 106034!!Platelet Degranulation Pathway 106050!!Rap1 Signaling Pathway 868086!!Rap1 Signaling Pathway 878042!!Regulation Of Actin Cytoskeleton Pathway 198874
ncbi summary :
This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012]
size :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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