product summary
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company name :
MyBioSource
product type :
protein
product name :
RAC2, 1-189aa, Human, His tag, E Coli
catalog :
MBS203366
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS203366 image 1
3 ug by SDS-PAGE under reducing coditions and visualized by coomassie blue stain.
product information
catalog number :
MBS203366
products type :
Recombinant Protein
products full name :
RAC2, 1-189aa, Human, His tag, E Coli
products short name :
[RAC2]
products name syn :
[Ras-related C3 botulinum toxin substrate 2.; EN-7; Gx; HSPC022; Ras-related C3 botulinum toxin substrate 2; EN 7; EN7; HSPC 022; p21 Rac 2; p21 Rac2; p21Rac2; RAC 2; Ras related C3 botulinum toxin substrate 2; Ras related C3 botulinum toxin substrate 3; Rho family small GTP binding protein Rac 2; Rho family small GTP binding protein Rac2; Small G protein.]
other names :
[ras-related C3 botulinum toxin substrate 2; Ras-related C3 botulinum toxin substrate 2; ras-related C3 botulinum toxin substrate 2; Rac family small GTPase 2; GX; Small G protein; p21-Rac2]
products gene name :
[RAC2]
other gene names :
[RAC2; RAC2; Gx; EN-7; HSPC022; p21-Rac2]
host :
E Coli
sequence positions :
[1-189aa]
sequence :
MGSSHHHHHH SSGLVPRGSH MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE VRHHCPSTPI ILVGTKLDLR DDKDTIEKLK EKKLAPITYP QGLALAKEID SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ PTRQQKRAC
purity :
> 95% by SDS-PAGE
form :
Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol 2mM EDTA, 2mM DTT, 0.1 M NaCl.
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 2-8°C for 1 week. For long term storage, aliquot and store at -20°C or -80°C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-Page
other info1 :
Antigen Species: Human. Tag Information: His-tag
products categories :
Signal Transduction
products description :
Rac2 is a small signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. Rac proteins play important roles in multiple cellular events, including actin cytoskeletal organization, cell proliferation and survival, cell cycle progression, and gene transcription regulation. Recombinant human RAC2 was expressed in E Coli and purified by using conventional chromatography techniques.
products references :
Ambruso DR., et al. (2000) Proc Natl Acad Sci u S A. 97 (9):4654-9. ; Faure J., et al. (2001) Biochimie. 83 (5):409-14.;
ncbi gi num :
4506381
ncbi acc num :
NP_002863
ncbi gb acc num :
NM_002872.4
uniprot acc num :
P15153
ncbi mol weight :
23.3 kDa (209aa), confirmed by MALDI-TOF.
ncbi pathways :
Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (1270303); B Cell Receptor Signaling Pathway (198909); B Cell Receptor Signaling Pathway (83081); B Cell Receptor Signaling Pathway (492); Beta-catenin Independent WNT Signaling Pathway (1269610); Chemokine Signaling Pathway (99051)
ncbi summary :
This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]
uniprot summary :
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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