catalog number :
MBS2033477
products type :
Recombinant Protein
products full name :
Recombinant Calmodulin Like Protein 5 (CALML5)
products short name :
[Calmodulin Like Protein 5]
products name syn :
[CLSP; Calmodulin-like skin protein]
other names :
[calmodulin-like protein 5; Calmodulin-like protein 5; calmodulin-like protein 5; calmodulin like 5; Calmodulin-like skin protein]
products gene name :
[CALML5]
other gene names :
[CALML5; CALML5; CLSP; CLSP]
uniprot entry name :
CALL5_HUMAN
form :
100mM NaHCO 3 , 500mM NaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
concentration :
Original Concentration: 200µg/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control, Immunogen, SDS-PAGE, WB. (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
Sequence Information
image2 heading :
SDS-Page
other info1 :
Source: Prokaryotic expression. Residues: Met1~Glu146. Tags: N-terminal His-Tag. Tissue Specificity: Skin, Hepatoma. Subcellular Location: Extracellular vesicular exosome. Traits: Freeze-dried powder. Predicted isoelectric point: 4.3. Predicted Molecular Mass: 19.6kDa. Accurate Molecular Mass: 20kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 100mM NaHCO 3 , 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi acc num :
NP_059118.2
ncbi gb acc num :
NM_017422.4
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Alcoholism Pathway (585563); Alcoholism Pathway (587116); Aldosterone Synthesis And Secretion Pathway (1272485); Aldosterone Synthesis And Secretion Pathway (1285075); Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Amphetamine Addiction Pathway (547607)
ncbi summary :
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq, Jul 2008]
uniprot summary :
CALML5: Binds calcium. May be involved in terminal differentiation of keratinocytes. Protein type: Calcium-binding. Chromosomal Location of Human Ortholog: 10p15.1. Molecular Function: calcium ion binding. Biological Process: epidermis development; signal transduction