product summary
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company name :
MyBioSource
product type :
protein
product name :
DAAO, 1-347aa, Human, His-tag, Recombinant, E Coli
catalog :
MBS203339
quantity :
0.05 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203339
products type :
Recombinant Protein
products full name :
DAAO, 1-347aa, Human, His-tag, Recombinant, E Coli
products short name :
DAAO
products name syn :
D-amino acid oxidase; DAMOX; DAO; OXDA; DAAO; D-amino acid oxidase DAO1; EC 1.4.3.3; MGC35381.
other names :
D-amino-acid oxidase; D-amino-acid oxidase; D-amino-acid oxidase; D-amino acid oxidase; D-amino-acid oxidase
products gene name :
DAAO
other gene names :
DAO; DAO; DAAO; OXDA; DAMOX; DAMOX; DAAO; DAMOX; DAO
uniprot entry name :
OXDA_HUMAN
sequence length :
347
sequence :
MGSSHHHHHH SSGLVPRGSH MRVVVIGAGV IGLSTALCIH ERYHSVLQPL DIKVYADRFT PLTTTDVAAG LWQPYLSDPN NPQEADWSQQ TFDYLLSHVH SPNAENLGLF LISGYNLFHE AIPDPSWKDT VLGFRKLTPR ELDMFPDYGY GWFHTSLILE GKNYLQWLTE RLTERGVKFF QRKVESFEEV AREGADVIVN CTGVWAGALQ RDPLLQPGRG QIMKVDAPWM KHFILTHDPE RGIYNSPYII PGTQTVTLGG IFQLGNWSEL NNIQDHNTIW EGCCRLEPTL KNARIIGERT GFRPVRPQIR LEREQLRTGP SNTEVIHNYG HGGYGLTIHW GCALEAAKLF GRILEEKKLS RMPPSHL
purity :
> 95% by SDS - PAGE
form :
Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 1mM DTT.
concentration :
0.5mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Redox Proteins
products description :
D-amino-acid oxidase (DAAO) is a peroxisomal enzyme which uses flavin adenine dinucleotide (FAD) as a cofactor and oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. It has been suggested that it is involved in acid base balance in the kidney or it could act as a detoxifying agent which removes D-amino acids accumulated during aging. Recombinant human DAAO protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
products references :
Kawazoe T., et al. (2006). Protein Sci. 15(12):2708-17. Chassande O., et al. (1994). J Biol Chem. 269(20):14484-9.
ncbi gi num :
148539837
ncbi acc num :
NP_001908
ncbi gb acc num :
NM_001917.4
ncbi mol weight :
41.6 kDa (367aa), confirmed by MALDI-TOF.
ncbi pathways :
Arginine And Proline Metabolism Pathway 82957!!Arginine And Proline Metabolism Pathway 323!!D-Arginine And D-ornithine Metabolism Pathway 82972!!D-Arginine And D-ornithine Metabolism Pathway 341!!Glycine, Serine And Threonine Metabolism Pathway 82949!!Glycine, Serine And Threonine Metabolism Pathway 313!!Glyoxylate Metabolism Pathway 160990!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Amino Acids And Derivatives Pathway 106169
ncbi summary :
This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
310 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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