catalog number :
MBS203337
products type :
Recombinant Protein
products full name :
GDF-10, 369-478aa, Human, Recombinant, E Coli
products short name :
GDF-10
products name syn :
Growth differentiation factor 10; BMP-3b; BMP3B; BIP; GDF-10; Growth differentiation factor 10 BMP 3b; BMP3B; Bone inducing protein; Bone morphogenetic protein 3b [Precursor]; GDF 10
other names :
bone morphogenetic protein 3B; Bone morphogenetic protein 3B; bone morphogenetic protein 3B; BIP; GDF-10; bone-inducing protein; growth differentiation factor 10; Bone-inducing protein; BIP; Growth/differentiation factor 10; GDF-10
products gene name :
GDF-10
other gene names :
GDF10; GDF10; BMP3B; BMP-3b; BMP3B; BMP-3B; BIP; GDF-10
uniprot entry name :
BMP3B_HUMAN
sequence :
MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R
purity :
> 95% by SDS - PAGE
form :
Liquid. In 10 mM sodium citrate (pH 3.5) containing 10% glycerol.
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli
products categories :
Hormones & Cytokines
products description :
GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Recombinant GDF10 protein was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Cunningham NS., et al. (1995) Growth Factors. 12(2):99-109. Ducy P., et al. (2000) Kidney Int. 57(6):2207-14.
ncbi gb acc num :
NM_004962.3
ncbi mol weight :
12.5 kDa (111aa), confirmed by MALDI-TOF.
ncbi pathways :
Adipogenesis Pathway 198832
ncbi summary :
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis. [provided by RefSeq, Jul 2008]