product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Peptidylglycine Alpha Amidating Monooxygenase (PAM)
catalog :
MBS2033171
quantity :
0.01 mg
price :
140 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2033171 image 1
image 2 :
MyBioSource MBS2033171 image 2
product information
catalog number :
MBS2033171
products type :
Recombinant Protein
products full name :
Recombinant Peptidylglycine Alpha Amidating Monooxygenase (PAM)
products short name :
[Peptidylglycine Alpha Amidating Monooxygenase]
products name syn :
[PAL; PHM; Peptidylamidoglycolate lyase; Peptidyl-Alpha-hydroxyglycine Alpha-amidating Lyase; Peptidylglycine Alpha-Hydroxylating Monooxygenase]
other names :
[peptidylglycine alpha-amidating monooxygenase, partial; Peptidyl-glycine alpha-amidating monooxygenase; Peptidylglycine alpha-hydroxylating monooxygenase (EC:1.14.17.3); PHMPeptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC:4.3.2.5)Alternative name(s):Peptidylamidoglycolate lyase; PAL]
products gene name :
[PAM]
other gene names :
[PAM; PAM; PHM; PAL]
uniprot entry name :
AMD_HUMAN
host :
E. coli
purity :
> 95%
form :
100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
concentration :
Original Concentration: 200 ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control; Immunogen; SDS-PAGE; WB. (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
Sequence Information
image2 heading :
SDS-Page
other info1 :
Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Phe21~Cys288. Tags: N-terminal His Tag. Traits: Freeze-dried powder
other info2 :
Predicted isoelectric point: 8.8. Predicted Molecular Mass: 33.7kDa. Accurate Molecular Mass: 34kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi gi num :
2661085
ncbi acc num :
AAB88190.1
uniprot summary :
PAM: Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. 6 isoforms of the human protein are produced by alternative splicing. Protein type: EC 4.3.2.5; Vesicle; Membrane protein, integral; Lyase; EC 1.14.17.3; Oxidoreductase. Chromosomal Location of Human Ortholog: 5q14-q21. Cellular Component: cell surface; extracellular space; integral to membrane; membrane; neuron projection; perikaryon; perinuclear region of cytoplasm; plasma membrane; secretory granule membrane; trans-Golgi network. Molecular Function: calcium ion binding; copper ion binding; L-ascorbic acid binding; peptidylamidoglycolate lyase activity; peptidylglycine monooxygenase activity; protein binding; protein kinase binding; zinc ion binding. Biological Process: central nervous system development; heart development; lactation; limb development; long-chain fatty acid metabolic process; maternal process involved in pregnancy; odontogenesis; ovulation cycle process; peptide amidation; protein amino acid amidation; protein homooligomerization; regulation of actin cytoskeleton organization and biogenesis; regulation of protein secretion; regulation of transcription from RNA polymerase II promoter; response to copper ion; response to drug; response to estradiol stimulus; response to glucocorticoid stimulus; response to hypoxia; response to pH; toxin metabolic process
size1 :
0.01 mg
price1 :
140 USD
size2 :
0.05 mg
price2 :
260
size3 :
0.1 mg
price3 :
400
size4 :
0.2 mg
price4 :
495
size5 :
0.5 mg
price5 :
955
size6 :
1 mg
price6 :
1415
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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