protein

Recombinant Proenkephalin (PENK)

MBS2033127

0.01 mg

140 USD

Recombinant Protein

Recombinant Proenkephalin (PENK)

[Proenkephalin]

[Preproenkephalin; Proenkephalin-A; Synenkephalin; Met-enkephalin; Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe]

[proenkephalin; Proenkephalin-A; proenkephalin-A; proenkephalin; SynenkephalinMet-enkephalinAlternative name(s):Opioid growth factor; OGF]

[PENK]

[Penk; Penk; Enk; Penk1; Penk2; Penk-rs; Penk-rs; Penk1; OGF]

PENK_RAT

E Coli

> 90%

Original Concentration: 200 ug/mL

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-PAGE, Western (WB), Positive Control, Immunogen. (May be suitable for use in other assays to be determined by the end user.)

SDS-Page

Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Glu25~Phe267. Tags: N-terminal His Tag . Subcellular Location: Secreted. Traits: Freeze-dried powder. Buffer: 100mMNaHCO 3 , 500mMNaCl, pH8.3, containing 0.01% SKL, 5% Trehalose.

Predicted isoelectric point: 5.3. Predicted Molecular Mass: 31.9kDa. Accurate Molecular Mass: 35kDa as determined by SDS-PAGE reducing conditions. Phenomenon explanation: The possible reasons that the actual band size differs from the predicted are as follows:. 1.Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post%translational modification: Phosphorylation, glycosylation, methylation etc. 4. Post%translation cleavage: Many proteins are synthesized as pro%proteins, and then cleaved to give the active form. 5. Polymerization of the target protein: Dimerization, multimerization etc. Usage: Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

259153

AAB24022.1

Class A/1 (Rhodopsin-like Receptors) Pathway (1333935); G Alpha (i) Signalling Events Pathway (1333966); GPCR Downstream Signaling Pathway (1333964); GPCR Ligand Binding Pathway (1333934); Peptide Ligand-binding Receptors Pathway (1333936); Signal Transduction Pathway (1333779); Signaling By GPCR Pathway (1333933)

neuropeptide hormone; plays a role in the responses to stress and pain perception [RGD, Feb 2006]

PENK: Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum. Belongs to the opioid neuropeptide precursor family. Protein type: Secreted, signal peptide; Hormone; Secreted

0.01 mg

140 USD

0.05 mg

255

0.1 mg

390

0.2 mg

480

0.5 mg

935

1 mg

1380