FABP3, 1-133aa, Human, His-tag, Recombinant, E Coli | MyBioSource MBS203298 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

FABP3, 1-133aa, Human, His-tag, Recombinant, E Coli

catalog :

MBS203298

quantity :

0.1 mg

price :

310 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS203298

products type :

Recombinant Protein

products full name :

FABP3, 1-133aa, Human, His-tag, Recombinant, E Coli

products short name :

FABP3

products name syn :

Fatty acid binding protein 3 muscle and heart; H-FABP; M-FABP; MDGI; FABP11; cardiac fabp; Fatty acid binding protein 3; muscle and heart Muscle fatty acid binding protein; 422 protein; Cardiac Fatty Acid Binding Protein; FABP 3.FABP3; Fatty acid binding protein 3 muscle; Fatty acid binding protein 3 muscle and heart; Fatty acid binding protein 3 muscle and heart mammary derived growth inhibitor; Fatty acid binding protein 11; Fatty acid binding protein heart; H FABP; Heart type fatty acid binding protein; M FABP; Mammary derived growth inhibitor; Mylein protein P2 homolog; O FABP; P2 adopocyte protein.

other names :

fatty acid-binding protein, heart; Fatty acid-binding protein, heart; fatty acid-binding protein, heart; Fatty acid-binding protein 3, muscle; fatty acid binding protein 11; heart-type fatty acid-binding protein; mammary-derived growth inhibitor; muscle fatty acid-binding protein; fatty acid binding protein 3, muscle and heart; Fatty acid-binding protein 3; Heart-type fatty acid-binding protein; H-FABP; Mammary-derived growth inhibitor; MDGI; Muscle fatty acid-binding protein; M-FABP

products gene name :

FABP3

other gene names :

FABP3; FABP3; MDGI; FABP11; H-FABP; M-FABP; O-FABP; FABP11; MDGI; H-FABP; MDGI; M-FABP

uniprot entry name :

FABPH_HUMAN

sequence length :

133

sequence :

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMVD AFLGTWKLVD SKNFDDYMKS LGVGFATRQV ASMTKPTTII EKNGDILTLK THSTFKNTEI SFKLGVEFDE TTADDRKVKS IVTLDGGKLV HLQKWDGQET TLVRELIDGK LILTLTHGTA VCTRTYEKEA

purity :

> 95% by SDS - PAGE

form :

Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

concentration :

1 mg/ml (determined by Bradford assay)

storage stability :

Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.

tested application :

SDS-PAGE

other info1 :

Antigen Species: Human. Tag: His-tag

other info2 :

Expression System: E Coli. Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)

products categories :

Transportation

products description :

FABP3 (Fatty acid binding protein 3) is also known as heart fatty acid binding protein and is a member of Fatty acid binding proteins (FABPs) which are a family of small, highly conserved, cytoplasmic proteins to bind long-chain fatty acids and other hydrophobic ligands. FABP3 is abundant in the myocardium and rapidly released from cardiomyocytes into the circulation after the onset of cell damage. Therefore, this protein has been proposed as an early biochemical marker of acute myocardial infarction and a sensitive marker for the detection and evaluation of myocardial damage in patients with heart failure. Recombinant FABP3 protein was expressed in E.coli and purified by using conventional chromatography techniques.

products references :

Troxler RF., et al. (2007). Hum Genet. 92(6):563-6. Zanotti G., et al. (1992). J Biol Chem. 267(26):18541-50.

ncbi gi num :

4758328

ncbi acc num :

NP_004093

ncbi gb acc num :

NM_004102.3

ncbi mol weight :

19.1 kDa (170aa), confirmed by MALDI-TOF.

ncbi pathways :

PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450)

ncbi summary :

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq, Jul 2008]

uniprot summary :

FABP3: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Protein type: Lipid-binding. Chromosomal Location of Human Ortholog: 1p33-p32. Cellular Component: extracellular space; cytosol; sarcoplasm. Molecular Function: protein binding; icosatetraenoic acid binding; cytoskeletal protein binding; long-chain fatty acid transporter activity. Biological Process: response to drug; negative regulation of cell proliferation; cholesterol homeostasis; regulation of fatty acid oxidation; fatty acid metabolic process; response to insulin stimulus; phospholipid homeostasis

size1 :

0.1 mg

price1 :

310 USD

size2 :

0.5 mg

price2 :

720

more info or order :

MyBioSource product webpage