product summary
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company name :
MyBioSource
product type :
protein
product name :
FABP5, 1-135aa, Human, Recombinant, E Coli
catalog :
MBS203293
quantity :
0.1 mg
price :
375 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203293
products type :
Recombinant Protein
products full name :
FABP5, 1-135aa, Human, Recombinant, E Coli
products short name :
FABP5
products name syn :
EFABP; E-FABP; PAFABP; PA-FABP; Fatty acid binding protein 5; Fatty acid-binding protein epidermal; FABP5; Fatty acid binding protein 5; fatty acid binding protein 5 (psoriasis-associated)
other names :
fatty acid-binding protein, epidermal; Fatty acid-binding protein, epidermal; fatty acid-binding protein, epidermal; epidermal-type fatty acid-binding protein; psoriasis-associated fatty acid-binding protein homolog; fatty acid binding protein 5 (psoriasis-associated); Epidermal-type fatty acid-binding protein; E-FABP; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; PA-FABP
products gene name :
FABP5
other gene names :
FABP5; FABP5; EFABP; KFABP; E-FABP; PAFABP; PA-FABP; E-FABP; PA-FABP
uniprot entry name :
FABP5_HUMAN
sequence length :
135
sequence :
MATVQQLEGR WRLVDSKGFD EYMKELGVGI ALRKMGAMAK PDCIITCDGK NLTIKTESTL KTTQFSCTLG EKFEETTADG RKTQTVCNFT DGALVQHQEW DGKESTITRK LKDGKLVVEC VMNNVTCTRI YEKVE
purity :
> 90% by SDS - PAGE
form :
Liquid in 20 mM Tris pH 8.0, 1 mM DTT, 20 % Glycerol
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli
products categories :
Serology
products description :
FABP5 is a member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to specifically bind fatty acids (FAs) with high affinity for stearic and linoleic acids. FABP5 is expressed in endothelial cells of the microvasculature of the placenta, heart, skeletal muscle, small intestine, lung, and renal medulla. FABP4 and FABP5 are closely related and both are expressed in adipocytes. Absence of FABP5 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Recombinant human FABP5 was expressed in E.coli and purified by conventional chromatography.
products references :
Hagens G., et al: (1999) Biochem.J ; 339 (Pt 2): 419-27. Hohoff C., et al: (1999) Biochemistry ; 38 (38): 12229-39.
ncbi gi num :
4557581
ncbi acc num :
NP_001435
ncbi gb acc num :
NM_001444.2
ncbi mol weight :
15kDa (135aa), confirmed by MALDI-TOF.
ncbi pathways :
PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); Signal Transduction Pathway (477114); Signaling By Retinoic Acid Pathway (1127533)
ncbi summary :
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011]
uniprot summary :
FABP5: High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Protein type: Lipid-binding. Chromosomal Location of Human Ortholog: 8q21.13. Cellular Component: nucleoplasm; cytoplasm; cytosol. Molecular Function: protein binding; transporter activity; fatty acid binding; lipid binding. Biological Process: epidermis development; phosphatidylcholine biosynthetic process; glucose metabolic process; glucose transport; lipid metabolic process
size1 :
0.1 mg
price1 :
375 USD
size2 :
0.5 mg
price2 :
925
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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