product summary
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company name :
MyBioSource
product type :
protein
product name :
FTL, 1-175aa, Human, Recombinant, E Coli
catalog :
MBS203292
quantity :
0.1 mg
price :
375 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203292
products type :
Recombinant Protein
products full name :
FTL, 1-175aa, Human, Recombinant, E Coli
products short name :
FTL
products name syn :
Ferritin L subunit; Ferritin; light polypeptide 1; FTL; Ferritin; light polypeptide 1 Ferritin H subunit; Ferritin heavy chain like; Ferritin heavy polypeptide 1; Ferritin light chain like; Ferritin light polypeptide; Ferritin; heavy polypeptide; FTH; FTH1; FTL protein.
other names :
ferritin light chain; Ferritin light chain; ferritin light chain; ferritin L subunit; ferritin L-chain; ferritin light polypeptide-like 3; ferritin, light polypeptide
products gene name :
FTL
other gene names :
FTL; FTL; LFTD; NBIA3; Ferritin L subunit
uniprot entry name :
FRIL_HUMAN
sequence length :
175
sequence :
MSSQIRQNYS TDVEAAVNSL VNLYLQASYT YLSLGFYFDR DDVALEGVSH FFRELAEEKR EGYERLLKMQ NQRGGRALFQ DIKKPAEDEW GKTPDAMKAA MALEKKLNQA LLDLHALGSA RTDPHLCDFL ETHFLDEEVK LIKKMGDHLT NLHRLGGPEA GLGEYLFERL TLKHD
purity :
> 90% by SDS - PAGE
form :
Liquid in 20 mM Tris-HCl (pH 7.5)
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli
products categories :
Serology
products description :
Ferritin is a large, iron-storage heteropolymeric protein composed of two subunit types, light (FTL) and heavy (FTH1) polypeptides, which is expressed in most kinds of cells and co-assemble in different proportion in a tissue-specific manner. Ferritin is composed of 24 self-assembled polypeptide subunits and is characterized by the capacity to remove Fe (II) from solution in the presence of oxygen. Recombinant human FTL was expressed in E.coli and purified by conventional chromatography techniques.
products references :
Baraibar MA., et al. (2008) J. Biol. Chem, 283(46), 31679-89. Santambrogio P., et al. (2000) Protein. Expr. Purif, 19(1), 212-8.
ncbi gi num :
20149498
ncbi acc num :
NP_000137
ncbi gb acc num :
NM_000146.3
ncbi mol weight :
20kDa (175aa)
ncbi pathways :
Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Clathrin Derived Vesicle Budding Pathway 119545!!Golgi Associated Vesicle Biogenesis Pathway 119546!!Integrated Pancreatic Cancer Pathway 711360!!Iron Uptake And Transport Pathway 187191!!Membrane Trafficking Pathway 106160!!Mineral Absorption Pathway 212237!!Mineral Absorption Pathway 212220!!Scavenging By Class A Receptors Pathway 833814!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
375 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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