catalog number :
MBS2032789
products full name :
Interleukin 6 (IL6) Polyclonal Antibody
products short name :
[Interleukin 6]
products name syn :
[MGI2-A; MGI2A; HGF; BSF2; HSF; IFNB2; B-Cell Stimulatory Factor-2; Hybridoma/Plasmacytoma Growth Factor; Hepatocyte Stimulating Factor; Cytotoxic T-Cell Differentiation Factor]
other names :
[interleukin-6; Interleukin-6; interleukin-6]
products gene name :
[IL6]
other gene names :
[IL-6; IL6; IL-6]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in PBS, pH7.4 containing 0.02% NaN3, 50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined
by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no
obvious degradation and precipitation were observed. The loss rate is less than 5% within the
expiration date under appropriate storage condition.
tested application :
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Immunoprecipitation (IP)
app notes :
Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
other info1 :
Organism Species: Sus scrofa; Porcine (Pig). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant IL6 (Gly30~Met212) expressed in 293F cel
ncbi acc num :
NP_001239358.1
ncbi gb acc num :
NM_001252429.1
ncbi pathways :
AGE-RAGE Signaling Pathway In Diabetic Complications (1320226); AGE-RAGE Signaling Pathway In Diabetic Complications (1319775); African Trypanosomiasis Pathway (194379); African Trypanosomiasis Pathway (194323); Amoebiasis Pathway (167313); Amoebiasis Pathway (167191); Antifolate Resistance Pathway (1440674); Antifolate Resistance Pathway (1440443); Cellular Senescence Pathway (1381258); Cellular Responses To Stress Pathway (1381246)
uniprot summary :
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation ().