catalog number :
MBS2032524
products full name :
Macrophage Receptor With Collagenous Structure (MARCO) Polyclonal Antibody
products short name :
[Macrophage Receptor With Collagenous Structure]
products name syn :
[SCARA2; Scavenger Receptor Class A, Member 2]
other names :
[macrophage receptor MARCO; Macrophage receptor MARCO; macrophage receptor MARCO; macrophage receptor with collagenous structure; Macrophage receptor with collagenous structure]
products gene name :
[MARCO]
other gene names :
[Marco; Marco; Ly112; Scara2; AI323439]
purity :
Antigen-specific affinity chromatography followed by Protein A affinitychromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
concentration :
0.56 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. TStability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2 ug/mL;1:280-1100. Immunohistochemistry: 5-20 ug/mL;1:28-110. Immunocytochemistry: 5-20ug/mL;1:28-110. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Mus Musculus(Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant MARCO (Gly366~Ser518) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2067129
ncbi acc num :
NP_034896.1
ncbi gb acc num :
NM_010766.2
ncbi pathways :
Binding And Uptake Of Ligands By Scavenger Receptors Pathway (1110598); Phagosome Pathway (153914); Phagosome Pathway (153859); Scavenging By Class A Receptors Pathway (1110600)
uniprot summary :
MARCO: Pattern recognition receptor (PRR). Binds Gram-positive and Gram-negative bacteria. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 1 1 E2.3. Cellular Component: collagen; integral component of membrane; intracellular; membrane; plasma membrane. Molecular Function: G-protein coupled receptor binding; scavenger receptor activity. Biological Process: apoptotic cell clearance; endocytosis; immune system process; innate immune response; negative regulation of adenylate cyclase activity; positive regulation of protein phosphorylation