product summary
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company name :
MyBioSource
product type :
protein
product name :
Wif-1, 29-379aa, Human, His-tag, Recombinant, Hi-5 cell
catalog :
MBS203250
quantity :
0.05 mg
price :
375 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203250
products type :
Recombinant Protein
products full name :
Wif-1, 29-379aa, Human, His-tag, Recombinant, Hi-5 cell
products short name :
Wif-1
products name syn :
Wnt inhibitory factor 1; WIF1; Wnt inhibitory factor 1
other names :
wnt inhibitory factor 1; Wnt inhibitory factor 1; wnt inhibitory factor 1; WNT inhibitory factor 1
products gene name :
Wif-1
other gene names :
WIF1; WIF1; WIF-1; WIF-1
uniprot entry name :
WIF1_HUMAN
sequence length :
379
sequence :
ADLGPPQEES LYLWIDAHQA RVLIGFEEDI LIVSEGKMAP FTHDFRKAQQ RMPAIPVNIH SMNFTWQAAG QAEYFYEFLS LRSLDKGIMA DPTVNVPLLG TVPHKASVVQ VGFPCLGKQD GVAAFEVDVI VMNSEGNTIL KTPQNAIFFK TCQQAECPGG CRNGGFCNER RICECPDGFH GPHCEKALCT PRCMNGGLCV TPGFCICPPG FYGVNCDKAN CSTTCFNGGT CFYPGKCICP PGLEGEQCEI SKCPQPCRNG GKCIGKSKCK CSKGYQGDLC SKPVCEPGCG AHGTCHEPNK CQCQEGWHGR HCNKRYEASL IHALRPAGAQ LRQHTPSLKK AEERRDPPES NYIWSGRLVP RGSHHHHHH
purity :
>80 % by SDS - PAGE
form :
Liquid. In PBS (pH 7.4) containing 10% glycerol, 1mM PMSF
concentration :
0.20mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: Hi-5. Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)
products categories :
Cancer
products description :
Wnt inhibitory factor 1, also known as Wif-1, is a secreted protein that binds to Wnt proteins involved in the embryonic development and cancer, and inhibits their activity. Wif-1 protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. It may be involved in mesoderm segmentation. This protein is found to be present in fish, amphibia and mammals. Recombinant human Wif-1 protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.
products references :
Wissmann C. et al. (2003) J. Pathol. 201:204-12. Cebrat M. et al. (2004) Cancer Lett. 206:107-13.
ncbi gi num :
111125011
ncbi acc num :
NP_009122.2
ncbi gb acc num :
NM_007191
ncbi mol weight :
40.5 kDa (369 aa)
ncbi pathways :
Disease Pathway 530764!!Presenilin Action In Notch And Wnt Signaling Pathway 137914!!RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway 1127632!!Signal Transduction Pathway 477114!!Signaling By WNT In Cancer Pathway 1127614!!Signaling By Wnt Pathway 106510!!TCF Dependent Signaling In Response To WNT Pathway 1127516!!Wnt Signaling Network Pathway 137962!!Wnt Signaling Pathway 83061!!Wnt Signaling Pathway 471
ncbi summary :
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010]
size :
0.05 mg
price :
375 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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