catalog number :
MBS203237
products type :
Recombinant Protein
products full name :
PDPN, 99-207aa, Human, His-tag, Recombinant, E Coli
products short name :
PDPN
products name syn :
T1A; GP36; GP40; Gp38; OTS8; T1A-2; HT1A-1; PA2.26; Lung type-I cell membrane-associated glycoprotein isoform a; Podoplanin; PDPN; Lung type-I cell membrane-associated glycoprotein isoform a AGGRuS; Glycoprotein 36 KD; Glycoprotein 36; gp 36; GP 38; GP 40; GP40; HT1A 1; HT1A1; hT1alpha1; Lung type I cell membrane associated glycoprotein; Lung type I cell membrane associated glycoprotein isoform a; hT1alpha2; PA2.26 antigen; T1 alpha; Lung type I cell membrane associated glycoprotein T1A 2; OTS 8; OTTHuMP00000009640; OTTHuMP00000044504; T1 ALPHA GENE; TIA 2; TIA2.
other names :
podoplanin isoform a; Podoplanin; podoplanin; PA2.26 antigen; PDPN; T1-alpha; glycoprotein 36; glycoprotein, 36-KD; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); podoplanin; Aggrus; Glycoprotein 36; Gp36; PA2.26 antigen; T1-alpha; T1A
products gene name :
PDPN
other gene names :
PDPN; PDPN; T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26; Gp36; T1A
uniprot entry name :
PDPN_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MASTGQPEDD TETTGLEGGV AMPGAEDDVV TPGTSEDRYK SGLTTLVATS VNSVTGIRIE DLPTSESTVH AQEQSPSATA SNVATSHSTE KVDGDTQTTV EKDGLSTVTL
purity :
> 95% by SDS - PAGE
form :
Liquid in 20 mM Tris pH 7.5, 0.1 M NaCl
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Cancer
products description :
Podoplanin(PDPN) is a small mucin-like transmembrane protein, widely expressed in various specialized cell types throughout the body. This is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. Recombinant human PDPN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography techniques.
products references :
Wicki A., et al. (2006) Br J Cancer. 96(1):1-5. Zimmer G., et al. (1999) Biochem J. 341, 277-84.
ncbi gb acc num :
NM_006474.4
ncbi mol weight :
13.4 kDa (130 aa), confirmed by MALDI-TOF.
ncbi summary :
This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]