catalog number :
MBS203227
products type :
Recombinant Protein
products full name :
SF20/IL25, 33-173aa, Human, His-tag, Recombinant, E Coli
products short name :
SF20/IL25
products name syn :
C19orf10; IL25; uPF0556; IL27; IL27w; Stromal cell-derived growth factor Chromosome 19 open reading frame 10; EuROIMAGE1875335; IL 25; IL 27; Interleukin 25; Interleukin 27 working designation; Interleukin25; R33729 1; R337291; SF20; Stromal cell derived growth factor; Stromal cell derived growth factor SF20; uncharacterized protein C19orf10 precursor.
other names :
UPF0556 protein C19orf10; UPF0556 protein C19orf10; UPF0556 protein C19orf10; interleukin 25; interleukin 27 working designation; interleukin-25; stromal cell-derived growth factor SF20; myeloid-derived growth factor; Interleukin-25; IL-25; Stromal cell-derived growth factor SF20
products gene name :
SF20/IL25
other gene names :
MYDGF; C19orf10; IL25; IL27; SF20; IL27w; C19orf10; R33729_1; EUROIMAGE1875335; IL25; IL-25
uniprot entry name :
CS010_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MSEPTTVAFD VRPGGVVHSF SHNVGPGDKY TCMFTYASQG GTNEQWQMSL GTSEDHQHFT CTIWRPQGKS YLYFTQFKAE VRGAEIEYAM AYSKAAFERE SDVPLKTEEF EVTKTAVAHR PGAFKAELSK LVIVAKASRT EL
purity :
> 95% by SDS - PAGE
form :
Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Hormones & Cytokines
products description :
SF20/25, originally identified as a product of bone marrow-derived stromal cells, was previously thought to support proliferation of lymphoid cells and was designated as interleukin. However, this activity has not been reproducible and the function of this protein is currently unknown. Recombinant human SF20/IL25 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, after refolding of the isolated inclusion bodies in a renaturation buffer.
products references :
Weiler T., et al. (2007) Arthritis Res Ther. 9, R30. Tulin E.E., et al. (2001) J. Immunol.167(11):6338-47.
ncbi gb acc num :
NM_019107.3
ncbi mol weight :
18 kDa (162 aa), confirmed by MALDI-TOF.
ncbi pathways :
IRE1alpha Activates Chaperones Pathway 105906!!Metabolism Of Proteins Pathway 106230!!Unfolded Protein Response (UPR) Pathway 105904!!XBP1(S) Activates Chaperone Genes Pathway 530771
ncbi summary :
The protein encoded by this gene was previously thought to support proliferation of lymphoid cells and was considered an interleukin. However, this activity has not been reproducible and the function of this protein is currently unknown. [provided by RefSeq, Jul 2008]