product summary
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company name :
MyBioSource
product type :
protein
product name :
CXCL1/GRO alpha, 35-107aa, Human, His-tag, Recombinant, E Coli
catalog :
MBS203223
quantity :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203223
products type :
Recombinant Protein
products full name :
CXCL1/GRO alpha, 35-107aa, Human, His-tag, Recombinant, E Coli
products short name :
CXCL1/GRO alpha
products name syn :
FSP; GRO1; GROA; MGSA; NAP-3; SCYB1; Chemokine (C-X-C motif) ligand 1; Growth-regulated alpha protein; Chemokine (C-X-C motif) ligand 1 / Growth-regulated alpha protein; CXCL1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity alpha); GRO1 oncogene (melanoma growth stimulating activity alpha); fibroblast secretory protein; SCYB1; MGSA-a
other names :
growth-regulated alpha protein; Growth-regulated alpha protein; growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha(1-73); GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); MGSA alpha; fibroblast secretory protein; melanoma growth stimulatory activity alpha; neutrophil-activating protein 3; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); C-X-C motif chemokine 1; GRO-alpha(1-73); Melanoma growth stimulatory activity; MGSA; Neutrophil-activating protein 3; NAP-3
other gene names :
CXCL1; CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a; GRO; GRO1; GROA; MGSA; SCYB1; MGSA; NAP-3
uniprot entry name :
GROA_HUMAN
sequence length :
107
sequence :
MGSSHHHHHH SSGLVPRGSH MASVATELRC QCLQTLQGIH PKNIQSVNVK SPGPHCAQTE VIATLKNGRK ACLNPASPIV KKIIEKMLNS DKSN
purity :
> 90% by SDS - PAGE
form :
Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli. Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)
products categories :
Hormones & Cytokines
products description :
CXCL1/GROa is a growth factor for melanoma cells and a chemotaxin for neutrophils. Similar to other alpha chemokines, this protein is potent neutrophil attractant and activator and is also active toward basophils. In addition, CXCL1 protein may be a therapeutic target as well as a diagnostic marker in ovarian cancer. Recombinant CXCL1 protein was expressed in E.coli and purified by using conventional chromatography techniques
products references :
Kawanishi H, et al. (2008) Clin Cancer Res., 2579-87. Yang HT, et al. (2008) Cell Signal, 375-80. Yang G, et al. (2006) Proc Natl Acad Sci u S A, 16472-7.
ncbi gi num :
4504153
ncbi acc num :
NP_001502
ncbi gb acc num :
NM_001511.3
ncbi mol weight :
10.1 kDa (94 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
ncbi pathways :
Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Chemokine Receptors Bind Chemokines Pathway 106359!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response Pathway 198794!!Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway 1127664
ncbi summary :
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
size :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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