product summary
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company name :
MyBioSource
product type :
protein
product name :
HIF1AN, 1-349aa, Human, Recombinant, E Coli
catalog :
MBS203207
quantity :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203207
products type :
Recombinant Protein
products full name :
HIF1AN, 1-349aa, Human, Recombinant, E Coli
products short name :
HIF1AN
products name syn :
Hypoxia-inducible factor asparagine hydroxylase; Factor inhibiting HIF-1; FIH1; Hypoxia-inducible factor 1; alpha subunit inhibitor Hypoxia inducible factor asparagine hydroxylase; Factor inhibiting HIF1; FIH 1; FLJ20615; FLJ22027; Hypoxia inducible factor 1 alpha inhibitor; Hypoxia inducible factor 1 alpha subunit inhibitor; Peptide aspartate beta dioxygenase; DKFZp762F1811; Hypoxia-Inducible Factor-1 Alpha Inhibitor
other names :
hypoxia-inducible factor 1-alpha inhibitor; Hypoxia-inducible factor 1-alpha inhibitor; hypoxia-inducible factor 1-alpha inhibitor; FIH-1; factor inhibiting HIF-1; factor inhibiting HIF1; hypoxia-inducible factor asparagine hydroxylase; peptide-aspartate beta-dioxygenase; hypoxia inducible factor 1, alpha subunit inhibitor; Factor inhibiting HIF-1; FIH-1; Hypoxia-inducible factor asparagine hydroxylase
products gene name :
HIF1AN
other gene names :
HIF1AN; HIF1AN; FIH1; FIH1; FIH-1
uniprot entry name :
HIF1N_HUMAN
sequence length :
349
sequence :
MAATAAEAVA SGSGEPREEA GALGPAWDES QLRSYSFPTR PIPRLSQSDP RAEELIENEE PVVLTDTNLV YPALKWDLEY LQENIGNGDF SVYSASTHKF LYYDEKKMAN FQNFKPRSNR EEMKFHEFVE KLQDIQQRGG EERLYLQQTL NDTVGRKIVM DFLGFNWNWI NKQQGKRGWG QLTSNLLLIG MEGNVTPAHY DEQQNFFAQI KGYKRCILFP PDQFECLYPY PVHHPCDRQS QVDFDNPDYE RFPNFQNVVG YETVVGPGDV LYIPMYWWHH IESLLNGGIT ITVNFWYKGA PTPKRIEYPL KAHQKVAIMR NIEKMLGEAL GNPQEVGPLL NTMIKGRYN
purity :
> 90% by SDS-PAGE
form :
Liquid. In 20 mM Tris-HCl buffer (pH 8.0)
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli
products categories :
Cell Cycle
products description :
Description: Hypoxia-inducible factor 1, alpha subunit inhibitor (HIF1AN), a member of the Fe2+ and 2-oxoglutarate-dependent dioxygenase superfamily, is protein that hydoxylates a specific asparagine residue (Asn-803) within the HIF1alpha C-terminal transactivation domain. In normoxia, the HIF1AN-mediated hydroxylation of the HIF1alpha transactivation domain results in blockage of the HIF1alpha-p300/CBP interaction and represses transcriptional activity of HIF1alpha-targeted genes. Recombinant human HIF1AN protein was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Fukuba H., et al. (2008) Neurosci Lett. 433(3):209-14. Li J., et al. (2007) Mol Cell Biol. 27(20):7345-53.
ncbi gi num :
148596936
ncbi acc num :
NP_060372
ncbi gb acc num :
NM_017902.2
ncbi mol weight :
40.2 kDa (349 aa), confirmed by MALDI-TOF.
ncbi pathways :
Cellular Response To Hypoxia Pathway 645259!!Cellular Responses To Stress Pathway 645258!!HIF-2-alpha Transcription Factor Network Pathway 137956!!Hypoxic And Oxygen Homeostasis Regulation Of HIF-1-alpha Pathway 138056!!Oxygen-dependent Asparagine Hydroxylation Of Hypoxia-inducible Factor Alpha Pathway 645261!!Regulation Of Hypoxia-inducible Factor (HIF) By Oxygen Pathway 645260
size :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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