catalog number :
MBS2032063
products full name :
Interleukin 1 Family, Member 9 (IL1F9) Monoclonal Antibody
products short name :
[Interleukin 1 Family]
products name syn :
[IL-1F9; IL36g; IL-1H1; IL-1RP2; IL1E; IL1H1; IL1RP2; Interleukin 36, Gamma; Interleukin-1 Homolog 1; Interleukin-1 epsilon; Interleukin 1-Related Protein 2]
other names :
[Interleukin-36 gamma; Interleukin-36 gamma; interleukin-36 gamma; interleukin 1 family, member 9; Interleukin-1 family member 9; IL-1F9]
products gene name :
[IL1F9]
other gene names :
[Il1f9; Il36g; Il36g; Il1f9; IL-1F9]
purity :
Protein A + Protein G affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH 7.4 containing 0.05%, Proclin-300, 50% Glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP).
app notes :
Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
DAB staining on IHC-P; Samples: Mouse Kidney Tissue
image5 heading :
Immunohistochemistry (IHC)
image5 description :
DAB staining on IHC-P; Samples: Mouse Lung Tissue
other info1 :
Organism Species: Mus musculus (Mouse). Source: Monoclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant IL1F9 (His5~Lys149 (Accession # Q8R460)) expressed in E.coli
ncbi pathways :
Cytokine Signaling In Immune System Pathway (1367586); Immune System Pathway (1367472); Signaling By Interleukins Pathway (1367594)
uniprot summary :
Functions as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2/IL1RL2. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP (). Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. May play a role in proinflammatory responses during particular neutrophilic airway inflammation. May be involved in the innate immune response to fungal pathogens. Induces the production of proinflammatory cytokines in bone marrow-derived dendritic cells (BMDCs), including IL-12, Il-1 beta, IL-6, TNF-alpha and IL-23. Involved in dendritic cell maturation by stimulating the surface expression of CD80, CD86 and MHC class II. Induces the production of IFN-gamma, IL-4 and IL-17 by cultured CD4+ T-cells and splenocytes.