product summary
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company name :
MyBioSource
product type :
protein
product name :
GADD45G, 1-159aa, Human, Recombinant, E Coli
catalog :
MBS203205
quantity :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203205
products type :
Recombinant Protein
products full name :
GADD45G, 1-159aa, Human, Recombinant, E Coli
products short name :
GADD45G
products name syn :
CR6; DDIT2; Growth arrest and DNA-damage-inducible gamma; Growth arrest and DNA-damage-inducible gamma; Cytokine responsive protein CR6; GADD45G; Growth arrest and DNA damage inducible gamma; GRP17
other names :
growth arrest and DNA damage-inducible protein GADD45 gamma; Growth arrest and DNA damage-inducible protein GADD45 gamma; growth arrest and DNA damage-inducible protein GADD45 gamma; DDIT-2; DNA damage-inducible transcript 2 protein; GADD45-gamma; cytokine-responsive protein CR6; gadd-related protein, 17 kD; growth arrest and DNA-damage-inducible, gamma; Cytokine-responsive protein CR6; DNA damage-inducible transcript 2 protein; DDIT-2
products gene name :
GADD45G
other gene names :
GADD45G; GADD45G; CR6; DDIT2; GRP17; GADD45gamma; CR6; DDIT2; DDIT-2
uniprot entry name :
GA45G_HUMAN
sequence length :
159
sequence :
MTLEELVACD NAAQKMQTVT AAVEELLVAA QRQDRLTVGV YESAKLMNVD PDSVVLCLLA IDEEEEDDIA LQIHFTLIQS FCCDNDINIV RVSGMQRLAQ LLGEPAETQG TTEARDLHCL LVTNPHTDAW KSHGLVEVAS YCEESRGNNQ WVPYISLQER
purity :
> 95% by SDS-PAGE
form :
Liquid. In 20 mM Tris-HCl buffer (pH 7.5)
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli
products categories :
Cell Cycle
products description :
GADD45G is a member of GADD45 family (GADD45alpha, beta, and gamma) that are nuclear proteins to interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45G protein responds to environmental stresses by mediating activation of p38/JNK pathway via MTK1/MEKK4 kinase and its transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. Recombinant GADD45G protein was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Takekawa M., et al. (1998) Cell 95(4), 521-30. Zerbini LF., et al. (2004) PNAS 101(37), 13618-23.
ncbi gi num :
5729836
ncbi acc num :
NP_006696
ncbi gb acc num :
NM_006705.3
ncbi mol weight :
17.8 kDa (160 aa), confirmed by MALDI-TOF.
ncbi pathways :
Cell Cycle Pathway 83054!!Cell Cycle Pathway 463!!DNA Damage Response Pathway 198788!!FoxO Signaling Pathway 921162!!IL12-mediated Signaling Events Pathway 137922!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!P38 MAPK Signaling Pathway 137943!!P53 Signaling Pathway 83055!!P53 Signaling Pathway 465
ncbi summary :
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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