SNAP23, 1-211aa, Human, Recombinant, E Coli | MyBioSource MBS203172 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

SNAP23, 1-211aa, Human, Recombinant, E Coli

catalog :

MBS203172

quantity :

0.05 mg

price :

310 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS203172

products type :

Recombinant Protein

products full name :

SNAP23, 1-211aa, Human, Recombinant, E Coli

products short name :

SNAP23

products name syn :

SNAP23A; SNAP23B; HsT17016; SNAP23; Synaptosomal-associated protein 23 isoform SNAP23A; Synaptosomal-associated protein 23 isoform SNAP23A SNAP 23; Synaptosomal associated protein; Synaptosomal associated protein 23; Synaptosomal associated protein 23kDa; Vesicle membrane fusion protein SNAP 23; Vesicle membrane fusion protein SNAP23.

other names :

synaptosomal-associated protein 23 isoform SNAP23A; Synaptosomal-associated protein 23; synaptosomal-associated protein 23; synaptosomal-associated protein, 23kD; vesicle-membrane fusion protein SNAP-23; synaptosomal-associated protein, 23kDa; Vesicle-membrane fusion protein SNAP-23

products gene name :

SNAP23

other gene names :

SNAP23; SNAP23; SNAP-23; SNAP23A; SNAP23B; HsT17016; SNAP-23

uniprot entry name :

SNP23_HUMAN

sequence length :

211

sequence :

MDNLSSEEIQ QRAHQITDES LESTRRILGL AIESQDAGIK TITMLDEQKE QLNRIEEGLD QINKDMRETE KTLTELNKCC GLCVCPCNRT KNFESGKAYK TTWGDGGENS PCNVVSKQPG PVTNGQLQQP TTGAASGGYI KRITNDARED EMEENLTQVG SILGNLKDMA LNIGNEIDAQ NPQIKRITDK ADTNRDRIDI ANARAKKLID S

purity :

> 90% by SDS - PAGE

form :

Liquid in 20mM Tris-HCl pH 8.0

concentration :

1 mg/ml (determined by Bradford assay)

storage stability :

Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.

tested application :

SDS-PAGE

other info1 :

Antigen Species: Human

other info2 :

Expression System: E Coli

products categories :

Neuroscience

products description :

SNAP23, a non-neuronal SNAP25 homologue, is a target SNARE ubiquitously expressed on the plasma membrane and other intracellular membranes. SNAP23 is widely believed to involve in exocytotic membrane fusion in most cells that do not express SNAP-25. Recombinant SNAP23 protein was expressed in E.coli and purified by using conventional chromatography techniques.

products references :

Okayama M.,et al. (2007) FEBS Lett. 581(24):4583-8. Faigle W., et al. (2000) Mol Biol Cell. 11(10):3485-94.

ncbi gi num :

18765729

ncbi acc num :

NP_003816

ncbi gb acc num :

NM_003825.3

ncbi mol weight :

23.3 kDa (211 aa), confirmed by MALDI-TOF.

ncbi pathways :

Clathrin Derived Vesicle Budding Pathway (119545); Insulin Signaling Pathway (198845); Membrane Trafficking Pathway (106160); Platelet Activation Pathway (952858); SNARE Interactions In Vesicular Transport Pathway (83057); SNARE Interactions In Vesicular Transport Pathway (467); Translocation Of GLUT4 To The Plasma Membrane Pathway (685554); Trans-Golgi Network Vesicle Budding Pathway (106165)

ncbi summary :

Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

SNAP23: a member of the SNAP-25 family of SNARE proteins. Structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternatively spliced isoforms have been described. Protein type: Vesicle. Chromosomal Location of Human Ortholog: 15q14. Cellular Component: nucleoplasm; SNARE complex; azurophil granule; specific granule; neuron projection; focal adhesion; mast cell granule; cytoplasm; plasma membrane; synapse. Molecular Function: SNAP receptor activity; protein binding; syntaxin binding. Biological Process: synaptic vesicle fusion to presynaptic membrane; protein transport; histamine secretion by mast cell; vesicle targeting; post-Golgi vesicle-mediated transport; synaptic vesicle priming

size1 :

0.05 mg

price1 :

310 USD

size2 :

0.25 mg

price2 :

720

more info or order :

MyBioSource product webpage