catalog number :
MBS203167
products type :
Recombinant Protein
products full name :
FABP7, 1-132aa, Human, Recombinant, E Coli
products short name :
FABP7
products name syn :
Fatty acid binding protein 7; FABP7; Fatty acid binding protein 7 B FABP; BFABP; BLBP; Brain lipid binding protein; DKFZp547J2313; FABP 7; FABPB; Fatty acid binding protein 7 brain; Fatty acid binding protein brain; OTTHuMP00000017119; Mammary derived growth inhibitor related; MRG.
other names :
fatty acid-binding protein, brain; Fatty acid-binding protein, brain; fatty acid-binding protein, brain; Hypothetical protein DKFZp547J2313; brain lipid binding protein; brain lipid-binding protein; brain-type fatty acid-binding protein; fatty acid-binding protein 7; mammary-derived growth inhibitor related; mammary-derived growth inhibitor-related; fatty acid binding protein 7, brain; Brain lipid-binding protein; BLBP; Brain-type fatty acid-binding protein; B-FABP; Fatty acid-binding protein 7; Mammary-derived growth inhibitor related
products gene name :
FABP7
other gene names :
FABP7; FABP7; MRG; BLBP; FABPB; B-FABP; LTR2-FABP7; BLBP; FABPB; MRG; BLBP; B-FABP
uniprot entry name :
FABP7_HUMAN
sequence :
MVEAFCATWK LTNSQNFDEY MKALGVGFAT RQVGNVTKPT VIISQEGDKV VIRTLSTFKN TEISFQLGEE FDETTADDRN CKSVVSLDGD KLVHIQKWDG KETNFVREIK DGKMVMTLTF GDVVAVRHYE KA
purity :
> 95% by SDS - PAGE
form :
Liquid in 25mM Tris pH 7.5, 1mM DTT, 2mM EDTA, 10% glycerol
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli
products categories :
Neuroscience
products description :
FABP7 (Fatty acid binding protein 7) is also known as brain fatty acid binding protein and is a member of Fatty acid binding proteins (FABPs) which are a family of small, highly conserved, cytoplasmic proteins to bind long-chain fatty acids and other hydrophobic ligands. FABP7 is expressed in radial glia by the activation of Notch receptors and binds DHA with the highest affinity among all of FABPs. Recombinant FABP7 protein was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Borchers T., et al. (1997).Prostaglandins Leukot. Essent. Fatty Acids. 57(1):77-84. Liu Rz., et al. (2003).Eur J Biochem. 270(4):715-25.
ncbi gb acc num :
NM_001446.3
ncbi mol weight :
14kDa (132aa), confirmed by MALDI-TOF.
ncbi pathways :
PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450)
ncbi summary :
The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]
uniprot summary :
FABP7: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Protein type: Cell cycle regulation; Cell development/differentiation; Lipid-binding. Chromosomal Location of Human Ortholog: 6q22-q23. Cellular Component: cell projection; cell soma; cytoplasm; nucleus. Molecular Function: transporter activity; lipid binding. Biological Process: negative regulation of cell proliferation; nervous system development; epithelial cell proliferation; prepulse inhibition; neurogenesis; transport; cell proliferation in forebrain