product summary
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company name :
MyBioSource
product type :
protein
product name :
ISG15, 1-157aa, Human, Calmodulin tag, Recombinant, E Coli
catalog :
MBS203150
quantity :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203150
products type :
Recombinant Protein
products full name :
ISG15, 1-157aa, Human, Calmodulin tag, Recombinant, E Coli
products short name :
ISG15
products name syn :
GIP2; uCRP; IFI15; ISG15; Interferon-stimulated gene; 15 kDa ubiquitin-like modifier; Interferon-stimulated gene; 15 kDa ubiquitin-like modifier IFI 15; Interferon alpha inducible protein; Interferon induced 15 kDa protein; Interferon induced 17 kDa protein; Interferon induced 17 kDa/15 kDa protein; Interferon Stimulated Gene 15; Interferon stimulated protein 15 kDa; ISG 15; ISG15 ubiquitin like modifier; ubiquitin cross reactive protein precursor.
other names :
ubiquitin-like protein ISG15; Ubiquitin-like protein ISG15; ubiquitin-like protein ISG15; interferon, alpha-inducible protein (clone IFI-15K); interferon-induced 17-kDa/15-kDa protein; interferon-stimulated protein, 15 kDa; ubiquitin cross-reactive protein; ISG15 ubiquitin-like modifier; Interferon-induced 15 kDa protein; Interferon-induced 17 kDa protein; IP17; Ubiquitin cross-reactive protein; hUCRP
products gene name :
ISG15
other gene names :
ISG15; ISG15; G1P2; IP17; UCRP; IFI15; IMD38; hUCRP; G1P2; UCRP; IP17; hUCRP
uniprot entry name :
ISG15_HUMAN
sequence length :
165
sequence :
MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAKG SMGWDLTVKM LAGNEFQVSL SSSMSVSELK AQITQKIGVH AFQQRLAVHP SGVALQDRVP LASQGLGPGS TVLLVVDKCD EPLNILVRNN KGRSSTYEVR LTQTVAHLKQ QVSGLEGVQD DLFWLTFEGK PLEDQLPLGE YGLKPLSTVF MNLRLRGG
purity :
> 98% by SDS - PAGE
form :
Liquid in 20mM Tris pH8.0, 0.1M NaCl, 1mM DTT
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: Calmodulin tag
other info2 :
Expression System: E Coli
products categories :
ubiquitination
products description :
The interferon-stimulated gene, 15 kDa (ISG15) is an interferon regulated gene that is induced as a primary response to diverse microbial and cell stress stimuli, and encodes the founding member of the ubiquitin-like protein family. ISG15 shares several common properties with other ubiquitin-like molecules (uBLs), but its activity is tightly regulated by specific signaling pathways that have a role in innate immunity. Recombinant human ISG15 was expressed in E.coli and purified by conventional chromatography techniques.
products references :
Narasimhan J., et al. (2005) J Biol Chem. 280(29):27356-65. Andersen JB., et al. (2006) Cytokine Growth Factor Rev. 17(6):411-21 .
ncbi gi num :
4826774
ncbi acc num :
NP_005092
ncbi gb acc num :
NM_005101.3
ncbi mol weight :
34kDa (308aa), confirmed by MALDI-TOF.
ncbi pathways :
Antiviral Mechanism By IFN-stimulated Genes Pathway 530760!!Cytokine Signaling In Immune System Pathway 366171!!ISG15 Antiviral Mechanism Pathway 530761!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!Interferon Signaling Pathway 187103!!Interferon Alpha/beta Signaling Pathway 187104!!Negative Regulators Of RIG-I/MDA5 Signaling Pathway 187102!!RIG-I-like Receptor Signaling Pathway 117292!!RIG-I-like Receptor Signaling Pathway 116128
ncbi summary :
The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012]
size :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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