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company name :
MyBioSource
product type :
protein
product name :
Casein Kinase 2beta (CK2beta, 1-215aa), Human, Recombinant, E Coli
catalog :
MBS203147
quantity :
0.05 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203147
products type :
Recombinant Protein
products full name :
Casein Kinase 2beta (CK2beta, 1-215aa), Human, Recombinant, E Coli
products short name :
Casein Kinase 2beta
products name syn :
PKCK2 Beta; PKCK2B; CK2N; CSK2B; MGC138222; MGC138224; G5A; Phosvitin; Casein Kinase 2 beta; Casein Kinase 2B; Casein Kinase 2 beta; Casein kinase 2 beta polypeptide; Casein kinase II subunit beta; CK II beta; CK2B; CSNK 2B; CSNK2B; G5A
other names :
casein kinase II subunit beta isoform 1; Casein kinase II subunit beta; casein kinase II subunit beta; CK II beta; CSNK2B-LY6G5B-532; CSNK2B-LY6G5B-560; Casein kinase II beta subunit; alternative name: G5a, phosvitin; casein kinase II b subunit splicing isoform 318; casein kinase II b subunit splicing isoform 660; casein kinase II b subunit splicing isoform 806; chimera CSNK2B-LY6G5B splicing isoform 532; chimera CSNK2B-LY6G5B splicing isoform 560; protein G5a; casein kinase 2, beta polypeptide; Phosvitin; Protein G5a
other gene names :
CSNK2B; CSNK2B; G5A; CK2B; CK2N; CSK2B; CK2N; G5A; CK II beta
uniprot entry name :
CSK2B_HUMAN
sequence length :
215
sequence :
MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA NQFVPRLYGF KIHPMAYQLQ LQAASNFKSP VKTIR
purity :
> 95% by SDS - PAGE
form :
Liquid. 20mM Tris pH8.0, 10% glycerol, 0.2M NaCl, 1mM DTT, 1mM EDTA
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli
products categories :
Signal Transduction
products description :
Casein Kinase 2 (CK2, also called PKCK2) is a ubiquitous Ser/Thr kinase expressed in all eukaryotes. CK2 is a tetramer composed of two catalytic kinase domains, alpha subunits, and two identical regulatory beta subunits. It has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes. The beta subunit itself does not have kinase activity, but confers stability to the CK2 alpha subunit and is involved in activity and substrate specificity. Recombinant human CK2beta was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Litchfield DW., et al. (2003). Biochem J. 369(1):1-15. unger GM., et al. (2004). Curr. Cancer Drug Targets 4(1):77-84.
ncbi gi num :
23503295
ncbi acc num :
NP_001311
ncbi gb acc num :
NM_001320.6
ncbi mol weight :
24.9kDa (215aa), confirmed by MALDI-TOF.
ncbi pathways :
ALK1 Signaling Events Pathway 137968!!Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Axon Guidance Pathway 105688!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Condensation Of Prometaphase Chromosomes Pathway 730316!!Developmental Biology Pathway 477129!!Disease Pathway 530764!!Epstein-Barr Virus Infection Pathway 585562
ncbi summary :
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
size :
0.05 mg
price :
310 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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