HSP105alpha 1-858aa, Human, His-tag, Recombinant, E Coli | MyBioSource MBS203142 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

HSP105alpha 1-858aa, Human, His-tag, Recombinant, E Coli

catalog :

MBS203142

quantity :

0.1 mg

price :

310 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS203142

products type :

Recombinant Protein

products full name :

HSP105alpha 1-858aa, Human, His-tag, Recombinant, E Coli

products short name :

HSP105alpha

products name syn :

HSPH1; Heat shock 105kDa/110kDa protein 1; HSP105alpha; HSP105-alpha; Heat shock 105kDa/110kDa protein 1 Antigen NY CO 25; DKFZp686M05240; Heat shock 105kD; Heat shock 105kD alpha; Heat shock 105kD beta; Heat shock 105kDa protein; Heat shock 105kDa protein 1; Heat shock 110kDa protein; Heat shock protein 105 kDa; HSP105A; HSP105B; HSP110; HSPH 1; KIAA0201; NY CO 25.

other names :

heat shock protein 105 kDa isoform 1; Heat shock protein 105 kDa; heat shock protein 105 kDa; antigen NY-CO-25; heat shock 105kD alpha; heat shock 105kD beta; heat shock 105kDa/110kDa protein 1; Antigen NY-CO-25; Heat shock 110 kDa protein

products gene name :

HSP105alpha

other gene names :

HSPH1; HSPH1; HSP105; HSP105A; HSP105B; NY-CO-25; HSP105; HSP110; KIAA0201

uniprot entry name :

HS105_HUMAN

sequence length :

858

sequence :

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSVV GLDVGSQSCY IAVARAGGIE TIANEFSDRC TPSVISFGSK NRTIGVAAKN QQITHANNTV SNFKRFHGRA FNDPFIQKEK ENLSYDLVPL KNGGVGIKVM YMGEEHLFSV EQITAMLLTK LKETAENSLK KPVTDCVISV PSFFTDAERR SVLDAAQIVG LNCLRLMNDM TAVALNYGIY KQDLPSLDEK PRIVVFVDMG HSAFQVSACA FNKGKLKVLG TAFDPFLGGK NFDEKLVEHF CAEFKTKYKL DAKSKIRALL RLYQECEKLK KLMSSNSTDL PLNIECFMND KDVSGKMNRS QFEELCAELL QKIEVPLYSL LEQTHLKVED VSAVEIVGGA TRIPAVKERI AKFFGKDIST TLNADEAVAR GCALQCAILS PAFKVREFSV TDAVPFPISL IWNHDSEDTE GVHEVFSRNH AAPFSKVLTF LRRGPFELEA FYSDPQGVPY PEAKIGRFVV QNVSAQKDGE KSRVKVKVRV NTHGIFTIST ASMVEKVPTE ENEMSSEADM ECLNQRPPEN PDTDKNVQQD NSEAGTQPQV QTDAQQTSQS PPSPELTSEE NKIPDADKAN EKKVDQPPEA KKPKIKVVNV ELPIEANLVW QLGKDLLNMY IETEGKMIMQ DKLEKERNDA KNAVEEYVYE FRDKLCGPYE KFICEQDHQN FLRLLTETED WLYEEGEDQA KQAYVDKLEE LMKIGTPVKV RFQEAEERPK MFEELGQRLQ HYAKIAADFR NKDEKYNHID ESEMKKVEKS VNEVMEWMNN VMNAQAKKSL DQDPVVRAQE IKTKIKELNN TCEPVVTQPK PKIESPKLER TPNGPNIDKK EEDLEDKNNF GAEPPHQNGE CYPNEKNSVN MDLD

purity :

> 90% by SDS - PAGE

form :

Liquid in 20 mM Tris pH 8.0, 50 mM NaCl

concentration :

1 mg/ml (determined by Bradford assay)

storage stability :

Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.

tested application :

SDS-PAGE

other info1 :

Antigen Species: Human. Tag: His-tag

other info2 :

Expression System: E Coli

products categories :

Heat Shock Proteins

products description :

Hsp105 is a mammalian member of the HSP105/110 family, a diverged subgroup of the HSP70 family. HSP105 exists as two isoforms, alpha and beta. Hsp105 alpha associates with Hsp70/Hsc70 as complexes in vivo and regulates the chaperone activity of Hsp70/Hsc70 negatively in vitro and in vivo. Recombinant His tagged HSP105 alpha was expressed in E.coli and purified by using conventional chromatography techniques.

products references :

Yamagishi N., et al. (2006) Exp Cell Res. 312(17):3215-23. Wang XY., et al. (2001) J Immunol. 166(1):490-7.

ncbi gi num :

42544159

ncbi acc num :

NP_006635

ncbi gb acc num :

NM_006644.3

ncbi mol weight :

100.9kDa (894aa)

ncbi pathways :

Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Protein Processing In Endoplasmic Reticulum Pathway (167325); Protein Processing In Endoplasmic Reticulum Pathway (167190); Scavenging By Class F Receptors Pathway (833816)

uniprot summary :

HSP105: a molecular chaperone of the heat shock protein 70 family. Has ATPase activity. Expressed at especially high levels in mammalian brain and has been shown to suppress apoptosis in neuronal cells and to prevent the aggregation of proteins following heat shock. Known to interact with a variety of proteins including alpha-tubulin and the androgen receptor. Two alternatively spliced isoforms have been described. Protein type: Heat shock protein; Chaperone. Chromosomal Location of Human Ortholog: 13q12.3. Cellular Component: nucleoplasm; microtubule; cytoplasm; extracellular region; cytosol. Molecular Function: protein binding; ATP binding; alpha-tubulin binding. Biological Process: receptor-mediated endocytosis; positive regulation of NK T cell activation; chaperone cofactor-dependent protein folding; positive regulation of MHC class I biosynthetic process; response to unfolded protein

size1 :

0.1 mg

price1 :

310 USD

size2 :

0.5 mg

price2 :

720

more info or order :

MyBioSource product webpage